Synthesis, Characterization and Structural Analysis of Two New Biguanide Complexes
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Date
2023-08
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Abstract
This study reports on the synthesis and characterization of two new coordination compounds of the active pharmaceutical ingredient metformin and transition metals. The cobalt compound with the formula [Co(Met)3][CoCl4]Cl·3H2O is a complex salt formed by a cationic Co(III) octahedral and anionic Co(II) tetrahedral subunits. The Cu(II) complex is represented by the formula [(Cu(Met)Cl)2-μ-Cl2] and is a dimeric compound with two chloride anions acting as a bridge, forming shared-edge square pyramidal units. Both compounds were characterized by single crystal X-ray diffraction, FT-IR spectroscopy and thermal analysis.
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Keywords
biguanide, metallo-drugs, coordination complexes, supramolecular
Citation
Pastrana-Dávila, A., Minotta, G., Ellena, J., Santiago, P. H. O., & D’Vries, R. F. (2023). Synthesis, Characterization and Structural Analysis of Two New Biguanide Complexes. Crystals, 13(8). https://doi.org/10.3390/cryst13081176