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La Importancia de los acidos grasos omega-3 en el manejo de la inflamación hepatica en perros. Revisión de literatura cientifica
(Universidad Santiago de cali, 2026-06-12) Jaramillo Donney´s,Veronica; Gutiérrez Gómez, Juan David(Director)
This technical report aims to highlight the importance of omega-3 fatty acids (EPA and DHA) in the management of chronic canine hepatic inflammation, emphasizing their anti-inflammatory, antioxidant, and pro-resolution action at the molecular level. It seeks to demonstrate the lack of a clear consensus on specific therapeutic dosages, coupled with variations in bioavailability depending on the supplement form and the typical dietary imbalance with excess omega-6 fatty acids, which complicates their clinical application. The report underscores the need for individualized prescribing that considers supplement quality, monitoring for risks such as coagulopathy, and using objective biomarkers (e.g., C-reactive protein) to assess response. Although the potential benefit of omega-3s includes reducing the dosage of hepatotoxic drugs, robust clinical evidence in dogs with liver disease remains scarce, with a lack of controlled studies. Furthermore, it seeks to conclude that optimal management requires precision medicine, addressing current methodological limitations and promoting future research that validates doses, biomarkers, and sustainable sources of omega-3 to ensure safety and efficacy in the nutritional support of canine hepatic disease..
Impacto de la suplementación con ácidos grasos omega-3 y omega-6 sobre la fisiología reproductiva y la fertilidad en bovinos (Bos taurus): revisión sistemática
(Universidad Santiago de Cali, 2026-06-09) Carabali Carabali, Cristian David; Cardona Tobar, Karen Melissa(Directora)
Reproductive efficiency in dairy production systems, especially in high-producing cows (Bos taurus), plays a fundamental role in the economic sustainability of these systems. However, it is compromised by factors such as negative energy balance during the transition period, which affects ovarian function and reduces fertility. In this context, omega-3 and omega-6 polyunsaturated fatty acids have been proposed as nutritional modulators of reproductive physiology. The aim of this study was to evaluate the impact of supplementation with these fatty acids on reproductive physiology and fertility in dairy cattle (Bos taurus). To this end, a systematic review was conducted following PRISMA guidelines, through a search of scientific literature published between 2016 and 2026 in specialized databases (PubMed, Scopus, Scielo, Web of Science, and Google Scholar); this review included controlled clinical trials, experimental studies, and systematic reviews. The results showed that omega-3 fatty acids contribute to improving conception rate, embryonic survival, and luteal function. In contrast, omega-6 fatty acids promote ovarian cyclicity and ovulation depending on the dose. Furthermore, it was identified that the reproductive response depends on the balance between both types of fatty acids, as well as the physiological and metabolic status of the animals. In this regard, supplementation with omega-3 and omega-6 may have positive effects on bovine reproduction, provided that an adequate balance is maintained to optimize fertility.
Impacto de la aflatoxina M1 en la salud bovina y su implicación en la seguridad alimentaria por contaminación de productos lácteos
(Universidad Santiago de Cali, 2026-09-02) Hernández Alarcón, Nathalie; Cabrera Matajira, Carlos Emilio(Director); Guarín Patarroyo,Camilo Ernesto(Director)
This systematic review analyzed 35 articles published between 2020 and 2025 on the presence and effects of aflatoxin M1 (AFM1) in the dairy chain, with the aim of assessing its impact on animal health and food safety. The studies originated in 22 countries in Asia, the Americas, Europe, and Africa and mainly comprised descriptive observational designs (65.7%), controlled experimental designs (22.8%), and technological or methodological validation designs (11.5%). Overall, more than 7,200 samples of raw and pasteurized milk, cheeses, and livestock feed were evaluated. The most commonly used methodologies included ELISA, HPLC, and LC-MS/MS, the latter two standing out for their greater sensitivity and specificity. The levels of AFM1 detected ranged from 0.01 to 1.2 µg/L, with values above the maximum permissible limit (0.05 µg/L) in 28% of the studies. The effects observed in cattle included liver damage, reduced milk production, and oxidative stress. In the area of food safety, a potential risk to consumers due to bioaccumulation and chronic exposure was evident. The methodological evaluation, based on the Cochrane tool, showed variability in the quality and bias of the studies, with experimental studies being the most rigorous. Overall, the findings underscore the need to strengthen surveillance systems, promote preventive practices in animal feed, and harmonize mycotoxin detection methods to ensure safety throughout the dairy supply chain.
La coproparasitología como herramienta para la vigilancia zoonótica: Revisión sistemática en poblaciones caninas en Colombia
(Universidad Santiago de Cali, 2026-08-31) Santana Rodriguez, Kenny Alejandra; Ospina Varón, Carlos Mario( Director)
This systematic review addresses the problem of zoonotic parasites transmitted by domestic canids in Colombia, a scenario where traditional coproparasitological techniques present critical sensitivity limitations in the face of alarming prevalence rates. The central objective was to analyze how the integration of quantitative methods, molecular epidemiology, and predictive models optimizes surveillance under the One Health approach. Methodologically, research on advanced technologies was synthesized, highlighting qPCR to quantify Parasite Genomes per Gram (PGG) and overcome the deficiencies of semi-quantitative methods such as Kato-Katz. Likewise, the role of molecular epidemiology in genotyping zoonotic strains (e.g., Giardia duodenalis) and detecting anthelmintic resistance was examined. The use of machine learning (ML) to mitigate epidemiological delays, and Quantitative Microbiological Risk Assessment (QMRA) to estimate human exposure risks within the framework of community surveillance, were also evaluated. The findings show that these tools achieve diagnostic sensitivities of up to 100%, allow for the anticipation of outbreaks with high precision, and generate substantial preventive economic benefits. In conclusion, the convergence of these technologies consolidates canine coproparasitology as a vital component of global biosecurity and public health, although it requires overcoming significant technical and governance challenges.
Asociación entre la falla en la transferencia de inmunidad pasiva y la aparición de hipoglucemia neonatal en potros
(Universidad Santiago de Cali, 2026-08-06) Rincon Valencia, Samuel; Martinez Lozano, Alexander(Director)
Failure of passive transfer of immunity (FPT) constitutes one of the main causes of neonatal morbidity and mortality in foals, while neonatal hypoglycemia represents a common metabolic alteration in this species. This systematic review, developed according to the PRISMA 2020 guidelines, aimed to analyze the available scientific evidence on the association between FPT and the occurrence of neonatal hypoglycemia in foals. A structured search was conducted in PubMed, ScienceDirect, Scopus, Redalyc, and Google Scholar, identifying 44 initial records, of which 21 studies met the eligibility criteria and were included in the qualitative synthesis. The reviewed studies describe two main pathophysiological pathways: a direct one of primary nutritional hypoglycemia due to colostrum deprivation, and an indirect one mediated by sepsis and systemic inflammatory response syndrome, which induces a hypermetabolic state and hepatic dysfunction, exacerbating the energy deficit. The reviewed evidence supports a synergistic interaction between the immunological and metabolic components of the equine neonate, highlighting the importance of early recognition of FPT through Brix refractometry and constant glucose monitoring.