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Universidad Santiago de Cali


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Actividad antibacteriana de extractos de semilla de hinojo (Foeniculum vulgare) obtenidos mediante extracción asistida por ultrasonido
(Universidad Santiago de Cali, 2026-06-23) Caro Alvarez, Santiago; Morales Morales, Jimmy Alexander(Director)
Foeniculum vulgare is a plant species recognized for the presence of secondary metabolites with potential biological activity. In the present study, the antibacterial behavior of the ethanolic extract obtained from F. vulgare seeds through ultrasound-assisted extraction was evaluated using broth microdilution and a complementary surface contact assay. The tests were performed against clinically relevant bacterial strains, including Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae. The results obtained through the broth microdilution method did not allow the determination of a minimum inhibitory concentration (MIC) against the evaluated strains under the experimental conditions used. However, the surface contact assay showed an inhibitory effect on bacterial growth in S. aureus and E. coli, as well as a partial reduction in the growth of K. pneumoniae, suggesting a behavior dependent on the evaluation method employed. Preliminary phytochemical characterization confirmed the presence of secondary metabolites such as tannins, phenolic compounds, diterpenes, and phytosterols in the evaluated ethanolic extract. The obtained results suggest that the physicochemical characteristics of some metabolites present in the extract could influence their behavior under different experimental systems, particularly in liquid-phase methodologies. Overall, the findings provide information regarding the antibacterial behavior of the ethanolic extract of F. vulgare and highlight the importance of employing complementary methodological approaches in the microbiological evaluation of plant-derived bioactive compounds.
Suplementación mineral como estrategia para mitigar la diseminación de E. coli O157:H7 en la cadena productiva bovina
(Universidad Santiago de Cali, 2026-09-03) Gomez Vargas, Natalia; Cabrera Matajira, Carlos Emilio(Director); Guarín Patarroyo, Camilo Ernesto(Director)
This systematic review evaluated mineral supplementation as a strategy to mitigate the spread of Escherichia coli O157:H7 in the cattle production chain. A total of 168 records were retrieved from five databases; after applying eligibility and exclusion criteria, 21 articles were selected, 11 of which were included in the discussion panel and the rest were used to enrich the methodological and introductory sections. The reviewed studies primarily used zinc in different forms (methionine, proteinate, oxide) and, to a lesser extent, copper, reporting positive effects on cattle health and productivity. Among the observed benefits were a reduction in the incidence and duration of diarrhea, increased daily weight gain, improved feed efficiency, and a strengthening of immune function and intestinal barrier integrity. Furthermore, zinc supplementation modulated the intestinal microbiota, promoting beneficial bacterial populations and reducing conditions conducive to E. coli O157:H7 colonization. However, some studies have shown risks such as co-selection of antimicrobial resistance in commensal bacteria. Overall, the evidence suggests that mineral supplementation, especially with highly bioavailable zinc, is promising for preventive strategies, but requires further studies with direct measurements of E. coli O157:H7, methodological standardization, and assessment of associated risks.
Valorización de especies vegetales nativas de las regiones Andina y Amazónica de Colombia para el desarrollo de productos con valor agregado
(Universidad Santiago de Cali, 2026-06-30) Cuevas Giraldo, Mariana; Suarez Osorio, Liseth (Director)
The trend toward replacing chemical products with natural ones has generated interest in studying native plants as a source of added value in industries such as medicine, food, and cosmetics. Thus, agri-food projects are being developed worldwide to strengthen producer organizations by utilizing these resources. This raises the question of how native Colombian plants can contribute to sustainable development and what benefits derive from their responsible use. To answer this, a systematic review of scientific literature on these species was conducted, focusing on the Andean and Amazonian regions, following the PRISMA guidelines. Scopus was used to obtain information, as it is one of the largest and most recognized databases in the research field, connecting databases such as SpringerLink, ScienceDirect, Wiley Online Library, Taylor & Francis, among many others that prioritize Q1 and Q2 indexed peer-reviewed journals. This was chosen to ensure the quality of the information and the diversity of articles, and to exclude obsolete and unreliable information, ensuring that the research is based on relevant and recent data. The analysis prioritized five key species: Mortiño, Cacay, Açaí, Sacha Inchi, and Camu Camu. It was concluded that Colombia has numerous plant species with properties useful in various industries. The Colombian Amazon stands out for its biodiversity, and many species have been identified that still require in-depth research into their uses and properties for application in value-added products. Therefore, the use of Colombian plants represents a great opportunity to strengthen the country's economy and promote biodiversity conservation. However, to achieve this, it is essential to ensure their responsible use, respecting local knowledge and avoiding practices that endanger ecosystems. Furthermore, more scientific research is needed to support their use and develop sustainable business models.
La Importancia de los acidos grasos omega-3 en el manejo de la inflamación hepatica en perros. Revisión de literatura cientifica
(Universidad Santiago de cali, 2026-06-12) Jaramillo Donney´s,Veronica; Gutiérrez Gómez, Juan David(Director)
This technical report aims to highlight the importance of omega-3 fatty acids (EPA and DHA) in the management of chronic canine hepatic inflammation, emphasizing their anti-inflammatory, antioxidant, and pro-resolution action at the molecular level. It seeks to demonstrate the lack of a clear consensus on specific therapeutic dosages, coupled with variations in bioavailability depending on the supplement form and the typical dietary imbalance with excess omega-6 fatty acids, which complicates their clinical application. The report underscores the need for individualized prescribing that considers supplement quality, monitoring for risks such as coagulopathy, and using objective biomarkers (e.g., C-reactive protein) to assess response. Although the potential benefit of omega-3s includes reducing the dosage of hepatotoxic drugs, robust clinical evidence in dogs with liver disease remains scarce, with a lack of controlled studies. Furthermore, it seeks to conclude that optimal management requires precision medicine, addressing current methodological limitations and promoting future research that validates doses, biomarkers, and sustainable sources of omega-3 to ensure safety and efficacy in the nutritional support of canine hepatic disease..
Impacto de la suplementación con ácidos grasos omega-3 y omega-6 sobre la fisiología reproductiva y la fertilidad en bovinos (Bos taurus): revisión sistemática
(Universidad Santiago de Cali, 2026-06-09) Carabali Carabali, Cristian David; Cardona Tobar, Karen Melissa(Directora)
Reproductive efficiency in dairy production systems, especially in high-producing cows (Bos taurus), plays a fundamental role in the economic sustainability of these systems. However, it is compromised by factors such as negative energy balance during the transition period, which affects ovarian function and reduces fertility. In this context, omega-3 and omega-6 polyunsaturated fatty acids have been proposed as nutritional modulators of reproductive physiology. The aim of this study was to evaluate the impact of supplementation with these fatty acids on reproductive physiology and fertility in dairy cattle (Bos taurus). To this end, a systematic review was conducted following PRISMA guidelines, through a search of scientific literature published between 2016 and 2026 in specialized databases (PubMed, Scopus, Scielo, Web of Science, and Google Scholar); this review included controlled clinical trials, experimental studies, and systematic reviews. The results showed that omega-3 fatty acids contribute to improving conception rate, embryonic survival, and luteal function. In contrast, omega-6 fatty acids promote ovarian cyclicity and ovulation depending on the dose. Furthermore, it was identified that the reproductive response depends on the balance between both types of fatty acids, as well as the physiological and metabolic status of the animals. In this regard, supplementation with omega-3 and omega-6 may have positive effects on bovine reproduction, provided that an adequate balance is maintained to optimize fertility.





