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Impacto negativo del consumo de carbohidratos no estructurales en la dieta del caballo: Revisión sistemática.
(Universidad Santiago de Cali, 2026-06-25) Mendoza Marin, Ana Sofia; Correa Toro, Nelson William(Director)
The increased use of energy concentrates and variations in pasture composition have increased horses' exposure to diets high in non-structural carbohydrates (CNE). This systematic review aimed to analyze recent scientific evidence on the impact of high CNE consumption on the metabolic and digestive health of horses. Studies published between 2015 and 2025 evaluating the physiological and clinical effects of diets rich in starches, simple sugars, and fructans were reviewed. The results show that excessive CNE consumption is associated with significant metabolic alterations, including sustained hyperinsulinemia, insulin resistance, and regional fat accumulation, factors closely related to equine metabolic syndrome. Likewise, several studies report that diets high in CNE promote rapid fermentation in the large intestine, which can alter the intestinal microbiota, induce dysbiosis, and trigger systemic inflammation. These alterations contribute to the development of digestive and metabolic disorders, especially endocrinopathic laminitis. Overall, the evidence supports the idea that controlling intake of non-structural carbohydrates in the equine diet is a key strategy for preventing metabolic and digestive disorders. These findings highlight the importance of implementing nutritional management practices to regulate CNE intake and preserve the horse's metabolic health.
Evaluación de los servicios ecosistémicos de la avifauna en agroecosistemas cafeteros colombianos: una revisión sistemática
(Universidad Santiago de Cali, 2026-06-24) Martínez Rodríguez, María Camila; Muñoz Valencia, Vanessa(Directora); Santamaría Velasco, Carlos Alfonso(Director)
The present study aimed to analyze the ecological role of avifauna in the environmental and productive sustainability of coffee agroecosystems in Colombia through a systematic literature review conducted in accordance with the guidelines of the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The search was carried out in indexed databases (Scopus, Web of Science, and ScienceDirect), complemented by regional sources (SciELO and Redalyc) and Google Scholar, covering publications from 2020 to 2025. A total of 312 records were identified, of which 247 were evaluated after duplicate removal, 86 were reviewed in full text, and 48 were included in the final synthesis. The results showed that shaded coffee systems account for the largest proportion of studies (65%) and exhibit higher bird diversity compared to sun-grown systems. The most frequently reported ecosystem service was biological pest control (72%), followed by seed dispersal (54%) and the use of birds as ecological indicators (48%). It is concluded that avifauna plays a fundamental role in ecological regulation, climate resilience, and the productive sustainability of coffee systems, highlighting the importance of promoting agroforestry models with a biodiversity-based approach.
Tratamiento de la ansiedad y trastornos del sueño con passiflora (Passiflora incarnata) y tilo (Tilia platyphyllos): Revisión sistemática
(Universidad Santiago de Cali, 2026-06-23) Becerra Figueroa, Henry; Burgos Restrepo, Luisa Fernanda; Cuadros Gutiérrez, Diego Gerardo(Director)
This review assessed the efficacy and safety of Passiflora incarnata and Tilia platyphyllos for anxiety and insomnia, focusing on extract standardization and applicability in pharmaceutical chemistry. Following PRISMA 2020 and the Cochrane Handbook, studies were searched in PubMed, Embase, CENTRAL, Scopus, Web of Science, and SciELO between 2019 and 2025. Bias was assessed using RoB 2/ROBINSI, and certainty was rated using GRADE. Narrative synthesis and meta-analysis were integrated where appropriate. Forty-five human studies were included, distributed among 27 randomized controlled trials, 6 quasi-experimental studies, and 12 observational studies, with 80% focusing on Passiflora and 20% on Tilia. This allowed for the estimation of clinically interpretable magnitudes for therapeutic decisions and the prescribing pathways. In insomnia, Passiflora showed increases in
total sleep time of approximately 23 minutes compared to placebo and improvements in PSQI/ISI scores at 30 days with good tolerability. In procedural anxiety, it was non-inferior to midazolam with less somnolence, and as an adjunct in benzodiazepine withdrawal, it was associated with a greater likelihood of sustained reduction. In contrast, Tilia presented limited evidence for monotherapy and was positioned as an adjunct. The main limitations were the heterogeneity of extracts, short durations, and multi-herb combinations. It is proposed to prioritize trials with extracts standardized for vitexin/isovitexin and tilianin, with a duration of ≥8–12 weeks and objective measures of sleep. In the field of pharmaceutical chemistry, this synthesis provides quality control criteria, analytical markers, and design guidelines that strengthen the traceability and clinical translatability of phytomedicines for anxiety and insomnia, optimizing decision-making and patient safety.
Estrategias de trazabilidad digital para la prevención del comercio ilegal de medicamentos: Revisión sistemática.
(Universidad Santiago de Cali, 2026-05-21) Reyes Madariaga, Nathalia; Restrepo Zapata, Jorge Humberto(Director)
This study focused on the issue of illegal drug trafficking, a problem that threatens public health due to the presence of counterfeit products in the pharmaceutical distribution chain. The objective of this research was to examine how digital traceability technologies, particularly serialization, blockchain, and the Internet of Things (IoT), can serve as tools to combat drug counterfeiting and improve the safety of the pharmaceutical system. The methodology used consisted of a systematic literature review, in which recent scientific studies from recognized databases were selected and analyzed, applying inclusion and exclusion criteria that prioritized the timeliness, relevance, and quality of the information. The findings showed that digital traceability technologies provide significant advantages compared to conventional methods, facilitating the unique identification of medicines, real-time tracking, and secure data recording. In addition, it was determined that serialization is the most common strategy in the regulatory field, while blockchain and the Internet of Things have high potential to increase transparency and control in the supply chain. It was concluded that the incorporation of these technologies constitutes an effective solution to reduce the illegal trade of medicines, improving traceability, the identification of irregularities, and the protection of public health. However, the need to strengthen applied research and promote their large-scale implementation was highlighted, especially in environments with technological limitations.
Beneficios de la Nanoencapsulación de activos mediante el sistema transportador lipídico nanoestructurado (NLC) como estrategia para optimizar la estabilidad de cremas cosméticas: Una Revisión Sistemática
(Universidad Santiago de Cali, 2026-06-24) Pérez Plaza, Juan Pablo; Tapie Taimal, Cristian Daniel; Ciro Monsalve, Yhors Alexander(Director)
The search for more effective, safe, and stable cosmetics has driven the development of formulations with multiple active ingredients; however, many of these compounds exhibit low stability when exposed to factors such as light, oxygen, temperature, pH, and humidity, which can compromise their efficacy, shelf life, and organoleptic characteristics. Nanostructured lipid carriers (NLCs) represent a promising strategy for optimizing the stability of active ingredients incorporated into cosmetic creams. The objective of this review was to analyze the benefits of nanoencapsulation using NLCs as a system for improving the physicochemical stability of cosmetic actives. To this end, a literature review was conducted in the PubMed, MDPI, ScienceDirect, and Springer databases, considering articles published between 2021 and 2026. An initial 1,285 records were identified, of which 49 studies met the inclusion and exclusion criteria. The results showed that the imperfect lipid matrix of NLCs, formed by the combination of solid and liquid lipids, promotes a greater carrying capacity, reduces the expulsion of the active ingredient during storage, and allows for more controlled release. Experimental studies reported particle sizes primarily between 50 and 300 nm, polydispersity indices below 0.5, and encapsulation efficiencies frequently exceeding 80% for antioxidants, retinoids, vitamins, UV filters, polyphenols, and plant extracts. Furthermore, improvements were observed in photostability, thermal stability, protection against oxidation, skin retention, and tolerability. It is concluded that NLCs constitute an effective technology for stabilizing cosmetic actives; however, their performance depends on the appropriate selection of lipids, surfactants, production method, and storage conditions.