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Prevalencia de bacterias de interés clínico en superficies de la clínica veterinaria de un zoológico en Colombia, 2026
(Universidad Santiago de Cali, 2026-06-26) Puerta Cardenas, Yohan Sebastian; Quiroz Mosquera, Nathalia; Duque Zapata, Juan Diego(Director); Peña Standlin, Juliana(Directora)
Veterinary clinics in zoos are highly complex microbiological environments where surfaces can act as reservoirs for bacteria with nosocomial and zoonotic potential. The objective of this study was to determine the prevalence of clinically significant bacteria on surfaces in a zoo veterinary clinic in Colombia during the first half of 2026. A descriptive cross-sectional study was conducted, involving the sampling of 14 surfaces distributed across five clinical areas using sterile swabs and culture on selective media (EMB, MSA, CT, and VRBD). An overall prevalence of 35.7% was observed (5 out of 14 positive surfaces). Klebsiella spp. was the most common genus (29%), followed by Staphylococcus spp. and Escherichia coli (14% each) and Pseudomonas spp. (7%). The reception area (75%) and the procedure room (50%) showed the highest levels of contamination. It is concluded that conditions exist that favor the presence of clinically significant bacteria in the evaluated environment, highlighting the need to strengthen biosafety protocols under the One Health approach.
Filmes eco-amigables de almidón reforzado con nanopartículas de Cu aplicados en la inhibición del crecimiento bacteriano.
(Universidad Santiago de Cali, 2026-06-12) Cuervo Estupiñan, Valeria; Mina Posu,Santiago; Chamorro Rengifo, Andrés Felipe(Director); Palencia Luna, Sixta(Directora)
Antimicrobial resistance represents a global crisis of great impact that threatens public health. In response to this issue, nanotechnology has emerged as an innovative and sustainable alternative, with metallic nanoparticles standing out due to their antimicrobial and wound-healing properties. The present study evaluated the green synthesis of copper metallic nanoparticles (CuNps) using lemon peel extract, followed by their incorporation into starch-based films. The formation of CuNps was confirmed by UV-Vis and DLS, obtaining a band at 229 nm and an average size of 197 nm. FTIR analysis revealed the presence of functional groups in both the CuNps and the polymeric material. The films exhibited adequate structural integrity and hydrophilic behavior, evaluated through swelling, solubility, and contact angle tests. In antimicrobial assays, inhibition zones ranging from 1.35 to 2.05 cm were recorded against both antibiotic-resistant and susceptible bacteria. The films exhibited physical and antimicrobial properties that support their use as wound dressings.
Estudio retrospectivo de la prevalencia y caracterización epidemiológica de enfermedades infecciosas en caninos, atendidos en cuatro clínicas veterinarias de la ciudad de Cali durante el año 2024
(Universidad Santiago de Cali, 2026-06-17) Gómez Vásquez, Claudia Marcela; Carmona Marín, Yolanda; Guarín Patarroyo, Camilo Ernesto(Director); Cabrera Matajira, Carlos Emilio(Director)
Infectious diseases in dogs are a frequent reason for consultation in veterinary clinical practice. The aim of this study was to determine the prevalence and epidemiologically characterize infectious diseases in dogs treated at four veterinary clinics in the city of Cali during 2024. An observational, descriptive, retrospective, and cross-sectional study was conducted based on a review of the medical records of dogs treated between January 1 and December 31, 2024. The variables analyzed included veterinary clinic, sex, age group, breed category, origin of the etiological agent, specific agent, and semester of care. The analysis included descriptive statistics and the Chi-square test. A total of 5,232 dogs were attended across the four clinics, of which 493 had infectious diseases, yielding an overall prevalence of 9.42%. The highest prevalence was observed at Mi Cachorrito (17.00%) and the lowest at Mundo Animal (7.90%). Regarding the etiological agent, parasitic origin predominated (68.8%), followed by bacterial (17.6%), viral (10.8%), and fungal (2.8%) origin. The most frequent specific agents were Cystoisospora (43.6%), Entamoeba histolytica (23.9%), Anaplasma platys (9.9%), canine parvovirus (9.1%), and Ehrlichia canis (4.3%). The most frequent age group was young adults (26.4%), and the distribution by sex was similar between females (50.3%) and males (49.7%). A significant association was found between the origin of the etiological agent and veterinary clinic (p < 0.001), as well as age group (p < 0.001), but not sex (p = 0.057) or semester of care (p = 0.237). It is concluded that infectious diseases in the evaluated population showed a predominance of parasitic agents and an etiological distribution influenced by veterinary clinic and age group, providing useful information for epidemiological surveillance and diagnostic guidance in dogs treated in Cali.
Nuevas estrategias tecnológicas implementadas en la reducción del comercio ilegal farmacéutico: Revisión sistemática
(Universidad Santiago de Cali, 2026-07-31) Padilla Pérez, Laura Ximena; Restrepo Zapata, Jorge Humberto(Director)
The illicit trade in medicines constitutes a growing global public health problem, associated with significant risks to patient safety and economic losses for health systems; drug counterfeiting is on the rise in countries where legislation regulating these illicit activities is weak and there is a lack of resources and measures to combat them. This study was conducted using a qualitative approach through a systematic literature review, with the objective of analyzing the available scientific evidence on the use of technological innovations to reduce the illegal trade in medicines, following the PRISMA statement guidelines; the literature search was conducted in recognized academic databases, such as ScienceDirect, PubMed, Scopus, SciELO, and Google Scholar. Studies associated with technologies applied to the detection, prevention, or control of counterfeit medicines were included, as well as research related to traceability in the pharmaceutical supply chain. The results highlighted new technologies such as blockchain, IoT, paper-based analytical devices (PAD), optical spectrophotometers (colorimeters), and X-ray fluorescence (XRF). However, limitations were identified regarding implementation costs, infrastructure requirements, regulatory barriers, and the need for staff training. It was also evident that none of the aforementioned strategies work alone or individually to eradicate the problem of counterfeit medicines; rather, a comprehensive approach is needed that combines administrative and technological tools, active surveillance, and continuous training of healthcare personnel. This combination or integration of approaches and strategies represents the most effective solution or pathway to reducing the circulation of counterfeit medicines in healthcare facilities.
Marcadores hematologicos y bioquimicos en la Erliquiosis canina segun la etapa de la enfermedad. Revisión sistemática.
(Universidad Santiago de Cali, 2026-05-25) Arcila Ramirez, Mayra Alejandra; Cardona Tobar, Karen Melissa(Directora)
Canine ehrlichiosis is a tick-borne infectious disease that affects dogs in tropical and subtropical regions and can cause hematological and biochemical alterations that reflect the systemic impact of the infection. The objective of this study was to analyze the most frequent hematological and biochemical markers in dogs with canine ehrlichiosis, considering the different clinical stages of the disease, through a systematic review of the scientific literature. To this end, research and selection of scientific articles was conducted in biomedical databases that reported hematological, biochemical, or biomarker alterations associated with Ehrlichia canis infection. The included studies were analyzed and organized into three main categories: hematological changes, biochemical alterations associated with organ involvement, and emerging biomarkers with diagnostic or prognostic potential. The results showed that the most frequent hematological alterations were thrombocytopenia, anemia, and leukopenia, which can present with varying intensity depending on the clinical phase of the disease and the presence of coinfections. Regarding biochemical changes, hepatic, renal, and protein metabolism alterations were identified, including increases in liver enzymes, changes in serum proteins, and alterations in renal parameters, suggesting multisystem organ involvement. Furthermore, recent studies have described emerging biomarkers, such as cardiac troponin, C-reactive protein, inflammatory cytokines, and urinary biomarkers, which could contribute to a more accurate assessment of disease severity and associated organ damage. Taken together, these findings demonstrate that integrating hematological, biochemical, and emerging biomarker parameters, along with molecular and serological diagnostic methods, can improve early detection, clinical monitoring, and pathophysiological understanding of Canine ehrlichiosis.