Medicina - Palmira
Permanent URI for this collection
Browse
Browsing Medicina - Palmira by Subject "Autoinmune"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Item Complicaciones en un paciente con esclerosis sistémica cutánea limitada (síndrome CREST): reporte de caso(Universidad Santiago de Cali, 2024) Riascos Ceballos, Segundo Alex; Cedeño, Diana Vanessa; Londoño, Mario Andrés (Director)Scleroderma is an autoimmune disease characterized by the accumulation of scar tissue and damage to internal organs such as the heart, blood vessels, lungs, stomach and kidneys. It is relatively uncommon and affects mostly women between the ages of 30 and 50. The main types of scleroderma are localized scleroderma and systemic scleroderma, which include subtypes such as CREST syndrome and diffuse cutaneous systemic scleroderma. The exact cause of these diseases is not clear, but genetic factors seem to be important in the disease. , it has also been suggested that exposure to certain chemicals could be a cause, but most patients do not have a history of exposure to chemicals(1). In this case report, a 76-year-old female patient with a history of scleroderma, Raynaud's syndrome, pulmonary hypertension, esophageal moniliasis, hyperuricemia, anemic syndrome, arterial hypertension, chronic kidney disease, who attends the emergency, is presented. real due to fatigue and shortness of breath when walking, necrosis in 3 toes of the left foot and edema in the lower limbs, multiple paraclinical tests, images and an abdominal aortogram plus selective arteriography of the lower limbs plus medicated balloon angioplasty in the left popliteal artery were performed. Immunosuppressive treatment is given, however it is not possible to obtain clinical improvement of the necrotic lesions, finally it is decided to perform amputation of the affected phalanges. With the clinical characteristics of the patient and the pathologies that she presents as background, it is considered that the events that occurred correspond to a complication of a CREST Syndrome.Item Esclerodermia cutánea localizada (morfea) en un infante: reporte de caso(Universidad Santiago de Cali, 2023) Palacio Herrera, John Edwin( Asesor); Riascos Ceballos, Gloris; Rodriguez Moncaleano, Nathalya; Arana Domínguez Daniel ( Director)Scleroderma is a rare disease with fewer than 3 new cases per 100,000 people per year. The localized form, more common in children and especially in females, chronically affects the skin and has an unknown cause, though it is linked to alterations in the extracellular matrix, immune system, and excess collagen production. This study presents the case of an 8-year-old boy with two skin lesions: a linear hyperpigmented lesion on the left mandibular branch extending to the labial commissure, and an oval depressed lesion on the left lumbar region, with no apparent cause or accompanying symptoms. After unsuccessful initial treatments, a skin biopsy was performed, confirming localized scleroderma of the morphea type.