Medicina - Palmira
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Item Esclerodermia cutánea localizada (morfea) en un infante: reporte de caso(Universidad Santiago de Cali, 2023) Palacio Herrera, John Edwin( Asesor); Riascos Ceballos, Gloris; Rodriguez Moncaleano, Nathalya; Arana Domínguez Daniel ( Director)Scleroderma is a rare disease with fewer than 3 new cases per 100,000 people per year. The localized form, more common in children and especially in females, chronically affects the skin and has an unknown cause, though it is linked to alterations in the extracellular matrix, immune system, and excess collagen production. This study presents the case of an 8-year-old boy with two skin lesions: a linear hyperpigmented lesion on the left mandibular branch extending to the labial commissure, and an oval depressed lesion on the left lumbar region, with no apparent cause or accompanying symptoms. After unsuccessful initial treatments, a skin biopsy was performed, confirming localized scleroderma of the morphea type.Item Perfil socioeconómico de los estudiantes admitidos al programa de medicina de la Universidad Santiago de Cali durante el período académico 2022-A y 2022-B(Universidad Santiago de Cali, 2023) González Parra, Alejandra; Rivas Delbasto, Valentina; Rojas Gutiérrez, Daniela; Arana Domínguez, Johan Daniel (Director)Item Síndrome de Leriche. Complicaciones de una enfermedad arterial periférica subdiagnosticada: reporte de caso(Universidad Santiago de Cali, 2023) Altamirano Jiménez, Vivian Nicole; Andrade Cifuentes, Ana Valentina; Sánchez Correa, Mauren Julieth; Sánchez Ospina, Sara Daniela; Rodríguez Bayona, Fernando (Director)Leriche syndrome is an aorto-iliac occlusive disease characterized by complete occlusion of arterial flow at the level of the abdominal aorta and/or its bifurcation. It is a generally underdiagnosed pathology, whose diagnosis is mainly based on a complete approach in terms of clinical history and complete physical examination, the main diagnostic instrument currently considered as gold standard is the angiotomography. Then is described the case of a 48 year old female patient with this diagnosis who concomitantly presented numerous risk factors whose clinical picture began with pain in the lower limbs associated with paresthesias and stump of the phalanx of the fifth finger of the left foot, in addition to intermittent claudication and absence of pulses in the lower extremities, was evaluated in integral way by numerous specialties who, although the clinical presentation of the patient was clear, were delayed establishing the diagnosis due to the absence of knowledge of the pathology. The high compromise of the patient required amputation of the fifth finger of her left foot. Our main interest is to raise awareness of this pathology that can be recognized more easily from the first contact with the patient we make a correct approach, including a complete physical examination and the correct use of diagnostic images that may be required and that allow us a definitive diagnosis and thus a timely intervention, in turn to prevent future complications.Item Endocarditis por Streptococcus equi spp: reporte de caso(Universidad Santiago de Cali, 2023) Imbacuan Moreno, Daniel Camilo; Villacorte Sánchez, Royman Gustavo; Quiceno Pulido, Mayerli Johana; Arana Domínguez, Johan Daniel (Director); Lozada Ramos, Heiler (Codirector)The present case report and literature review support that, although severe human infections with Streptococcus equi spp are rare, they have a poor prognosis and lead to high patient morbidity and mortality; cases have been documented mainly in patients with close contact with animals, especially horses, and with consumption of unpasteurized dairy products. Worldwide, gram-positive bacteria account for approximately 80% of cases of native valve infective endocarditis (IE). These bacteria include Staphylococcus aureus in 35 to 40% of native IE cases, streptococci in 30 to 40% (Streptococcus viridans in approximately 20%, Streptococcus gallolyticus [formerly S. bovis] and other streptococci in approximately 15%, within this percentage streptococcus equi is included), and enterococci in 10% [2]. We present the case of a patient with infective endocarditis due to streptococcus equi spp, from which we will describe the clinical, microbiological and imaging diagnostic approach that are useful, as well as the current therapeutic approach for the management of infective endocarditis due to this germ.Item Esclerodermia cutánea localizada (morfea) en un infante: reporte de caso(Universidad Santiago de Cali, 2023) Palacio Herrera, John Edwin; Riascos Ceballos, Gloris; Rodríguez Moncaleano, Nathalya; Molano Agudelo, Pedro (Director)Scleroderma is a rare disease, the estimated frequency never exceeds 3 new cases per 100,000 people per year (1). Localized scleroderma is the most frequent form in children and mainly affects women, chronically compromising the skin; Its etiology is idiopathic and its pathogenesis has involved alterations in the extracellular matrix, immunological disorders, and hyperproduction of collagen (2). In the following investigation, the case of an 8-year-old male patient who comes with his parents for dermatological evaluation was evaluated due to presenting a clinical picture of one year of evolution consisting of the appearance of 2 lesions with a linear hyperpigmented pattern located in the left mandibular ramus. up to the labial commissure and the other oval depressed lesion of approximately 1 cm in diameter in the left lumbar region, with no apparent trigger or accompanying symptoms; at the beginning the diagnosis is unknown, he receives therapeutic intervention with DHEMS sunscreen with repellent, Cromus cream at 0.03%, Desonide cream at 0.05%, Anestecin cream, Cefadroxil suspension 500 mg, without obtaining satisfactory results, therefore a skin biopsy whose results were compatible with localized morphea scleroderma. Conclusion: This case exemplifies the relevance of having up-to-date and accurate knowledge regarding the differential diagnosis of skin lesions, as well as the importance of knowing how to identify them and start pharmacological treatment early.Item Suicidio en la infancia análisis bibliométrico del suicidio en la infancia entre los años 2016 al 2022(Universidad Santiago de Cali, 2023) Córdoba Mosquera, María Fernanda; Cárdenas Sandoval, María Camila; Montalvo Quintero, Juan Camilo; Castro Penagos, Lilia Julieta (Directora)The objective of this research was to characterize the scientific production on child suicide worldwide in the period 2016 to 2022, through a bibliometric analysis in the databases in 3 PubMed/MEDLINE (National Center for Biotechnology Information) databases. /Medical Literature Analysis and Retrieval System Online), Web of Science and Scopus using the main word “Child suicide”. The number of articles reviewed was 15,161 in the first filter. When carrying out the second filter, a compilation of the results was carried out in all the chosen databases, obtaining 86 articles. being the United States the country with the highest production with 34 published works. To date, there are more than 4,000 articles published in the field of child suicide knowledge to date, noting that Scopus is the database with the most publications on this topic; however the PubMed database does not have many of these articles in its database. One of the antecedents found on the subject is "Bibliometric analysis of the scientific production on suicide in children in the period 1985-2005" The objective of this research was to review the scientific production on suicide in the child population, through a bibliometric analysis of the articles published during the period 1985-2005, in the Lilacs, Medline, Ebsco Host and Ovid databases. The number of articles reviewed was 84, with the United States being the country with the highest production, with 65.85% of the papers published. Finding, as in our research, that this country continues to be the one that carries out the most research on the subject (Palacios et al., 2007). The research contributes to medicine since the bibliometric indicators are metrics at the service of scientific activity, as a complement to the evaluation by experts, it allows to inquire about the current state of research on child suicide, being able to facilitate researchers to delve into relevant issues.Item Dextrocardia y bloqueo auriculoventricular completo con implantación de marcapaso en adulto mayor: reporte de caso(Universidad Santiago de Cali, 2023) Fajardo Valdés, Natalia; Meneses Ortega, Carolina; Yela Girón, Lina Fernanda; Moreno Moriano, Diego Fernando (Director)Item Fagoterapia: una nueva alternativa terapéutica en la resistencia a los antibióticos - revisión sistemática(Universidad Santiago de Cali, 2023) Osorio Hernández, Sofía; Perea Gordillo, Laura Sofía; Arana Domínguez, Johan Daniel (Director); Molano Agudelo, Pedro (Codirector)In 1917, the British microbiologist Frederick Twort discovered bacteriophages and described them as viruses that infect bacteria; these have been the subject of investigation for use in therapy against antibiotic-resistant bacterial diseases. Bacteriophages are viruses that infect and parasitize bacteria. Through this, phage therapy is a medical technique used to combat bacterial infections (1) The function of a bacteriophage in phage therapy is within the bacterium, it reproduces and replicates, causing the lysis or rupture of the bacterial cell and produces the release of new bacteriophages. These will be specific for certain types of bacteria and bind to them via proteins on their surface (1). As is well known, resistance to antibiotics has become a global problem that has been increasing in recent years and has led to the increasingly frequent appearance of multi-resistant bacterial pathogens that poses a therapeutic and therapeutic dilemma for medical personnel. a constant challenge for its correct approach. Therefore, the use of phage therapy as a non-antibiotic therapeutic alternative is being considered and practiced in some parts of the world (2). Therefore, we consider it important to address this novel topic in academic and scientific discussion scenarios to raise questions in the medical community. In this sense, we are going to carry out a systematic review following the prisma guidelines, based on searches in the main databases such as Pubmed, Sciencedirect, Taylor and Francis, Oxford academy, Scopus; where articles resulting from systematic reviews, randomized clinical studies and research articles will be included, which have been published between 2017 and 2023 in languages such as English, Spanish and French. From which we hope to gather evidence for the use of phage therapy in antibiotic resistance. The systematic review was in charge of analyzing phagotherapy oriented to antibiotic resistance where it was reflected that Europe is the region with the greatest presence in research, followed by America, Asia and Africa. Taking into account the global threat posed by antibiotic resistance in public health, so it is born as an alternative due to its greater specificity, low rate of side effects, low cost of production in addition to presenting Although it has several limitations, which makes it difficult to use in clinical practice, such as the lack of extensive studies to understand the genome and properties of phages, the lack of a standard regulatory framework and the importance of selecting the appropriate bacteriophages to treat a specific bacterial infection.Item Impacto de las intervenciones educativas en el manejo del dolor y variables biopsicosociales en adultos con dolor oncológico. Revisión sistemática(Universidad Santiago de Cali, 2023) Henao Bermúdez, Laura Isabel; Domínguez Palacios, Lawrence; Ordoñez Mora, Leydi Tatiana (Directora)Item Endocarditis infecciosa por Streptococo gallolyticus tipo: pasteurianus en un paciente de 13 años: caso clínico(Universidad Santiago de Cali, 2023) Londoño Ospina, Lisa Manuela; Parra Lozada, Laura Alejandra; Guzmán Sandoval, Juan Camilo; Salcedo Libreros, Luis Felipe (Director)Introduction: infective endocarditis (IE) is an inflammatory and infectious process that affects the endocardium, predominantly at the valvular level, secondary to bacterial or fungal hematogenous colonization, its clinical expression is variable, depending on the extent of local heart disease, degree affectation to other organs and causal agent; The diagnosis is established through the clinical history, physical examination, blood cultures, laboratory tests, and echocardiogram with subsequent identification of the microorganism and initiation of specific and targeted antibiotic treatment. Objective: To describe the clinical case of an adolescent patient with infective endocarditis due to streptococcus gallolyticus, a microorganism that only causes 7% of IE cases, with characteristic clinical criteria of the disease. Clinical case: The case of a 13-year-old male patient is presented, who was admitted to the emergency department on June 9, 2022 due to a clinical picture of 5 days of evolution consisting of temperature rises quantified at approximately 39ºC, cervical pain, headache intense and paresthesia in the lower limbs, associated with changes in the state of consciousness, a transthoracic echocardiogram was performed, which revealed emboli in the aortic valve, bileaflet aorta with data suggestive of severe insufficiency with a high probability of systemic embolism and secondary severe aortic insufficiency. start antibiotic treatment with ceftriaxone 1.5 g every 12 hours diluted in 10cc of saline solution and gentamicin 120 mg every 8 hours depending on sensitivity and isolated microorganism, Streptococcus gallolyticus pasteurianus.Item Resistencia antifúngica a los antimicóticos usados en Colombia: agentes etiológicos y frecuencia de aislamientos - revisión sistemática(Universidad Santiago de Cali, 2023) Cuenca Casanova, Laura Daniela; Moreno Fuelantala, Johana Lisbeth; Guerra Ordoñez, Dayra Valentina; Caicedo Bejarano, Luz Dary (Directora)Item Ecthyma gangrenosum of fungal origin: case report(Universidad Santiago de Cali, 2023) León Sánchez, Germán Andrés; Arana Domínguez, Johan Daniel (Director); Lozada Ramos, Heiler (Codirector)Item Riesgos, beneficios e indicaciones del cannabis en el tratamiento del Parkinson, revisión sistemática(Universidad Santiago de Cali, 2023) Rincón Valencia, Daniela; Arroyave Muñoz, Daniela; Cobo Restrepo, Silvana; Arana Domínguez, Johan Daniel (Director)Parkinson's disease is a neurodegenerative disorder that has multiple motor and non-motor manifestations. The pathological process begins years or decades before the onset of non-motor symptoms, at which time other symptoms develop that very often precede the clinical onset(1). As for cannabis, it has been studied as a therapeutic treatment since it has an indisputable compensatory role on endogenous cannabinoids and acts as a neuromodulator and neuroprotector in some Parkinson's situations, which affects a series of receptors, including cannabinoid receptors (CB1R). and CB2R), among others. Through the bibliographic compilation established in this systematic review, with eligibility criteria using articles between 2015 and 2022 that are freely available in English and Spanish, it is intended to describe the benefits, risks, and indication of uses of medicinal cannabis in Parkinson's treatment, with the intention of updating the treatments applied to Parkinson's and improving the quality of life of people who suffer from it.Item Síndrome de activación macrofagocítica en un paciente pediátrico. Reporte de caso(Universidad Santiago de Cali, 2023) Arias Eusse, María Camila; Basto Domínguez, Carolina; Montoya Hurtado, Carolina; Arana Domínguez, Johan Daniel (Director)Hemophagocytic syndrome (SHF), also known as hemophagocytic lymphohistiocytosis (HLH), usually occurs mainly in childhood being a serious disease resulting from a deregulation of the immune system either by infectious causes, neoplastic, genetic, metabolic or rheumatological leading to an exaggerated immune response. This syndrome acts quickly and puts the patient’s life at risk, so the diagnosis must be based on clinical and paraclinical criteria and then HLH-2004 protocol must be initiated. This case report will be important to make this pathology visible since it is uncommon, which occurs in all age groups, but mainly in pediatric age, has an incidence of 1 in 50,000 live births and varies by geographical region (1). We present the case of a minor patient with a diagnosis of Hemophagocytic Syndrome in whom paraclinics and diagnostic images are taken, biopsy and bone marrow aspirate plus study of the Cerebrospinal Fluid.Item Síndrome de Williams Beuren en lactante mayor con retraso pondoestatural sin presencia de cardiopatía congénita: reporte de caso(Universidad Santiago de Cali, 2023) Bahena Marín, Valentina; Campo Gallego, Vanessa; Restrepo Gaviria, Deisy Lorena; Kanan Mohamed, Ahmad Talat (Director)Williams disease is a genetic disorder of neurological development, which includes different clinical manifestations such as growth and intellectual retardation, congenital heart disease and distinctive facial features, with an incidence of 1/10,000 live births in the world¹. Case report of an older infant, with a perinatal history of intrauterine growth retardation (IUGR), threatened preterm delivery and breech position, for which she required a cesarean section in a highly complex clinic with availability neonatal intensive care unit. In which said pathology was suspected, due to the presence of phenotypic characteristics such as epicanthal fold, wide nasal bridge, thick lips, bitemporal narrowing, being diagnosed with Williams syndrome, through genetic and imaging tests in which it is important to highlight that no one of the most frequent characteristics of this syndrome, which is congenital heart disease, the highlight in this case being its marked weight, height and psychomotor retardation. The objective of this report is to present the main clinical characteristics that guide the early diagnosis of Williams Syndrome, which belongs to the group of rare diseases. So that health personnel can provide comprehensive management and thus generate greater visibility of this disease in the scientific community.Item Trombastenia de Glanzmann en paciente pediátrico, reporte de caso(Universidad Santiago de Cali, 2023) Cárdenas Ruiz, Brian; Hernández, Maryuri; Portilla Velásquez, Kevin; Salcedo, Luis Felipe (Director)Glanzmann's thrombasthenia is a disease caused by alterations in platelet membrane receptors that causes symptoms such as significant bleeding and bruising in the patient's facial area, particularly around the eyes and mouth. This disease is considered a rare disease and affects 1 x 1,000,000 people and occurs to a greater extent in certain areas of Africa and Asian countries such as Pakistan, it is a disease that is difficult to diagnose given its unusual presentation and therefore requires tests specialized and complex to achieve an adequate differential diagnosis (3). Treatments should be focused on ensuring that duly diagnosed patients have good dental hygiene to avoid bleeding situations such as gingivitis and are aware of situations in which the disorder could have an incidence, such as menstrual bleeding in women. In case of bleeding, intravenous platelets are used as a therapeutic measure. This case report describes a case of a pediatric patient diagnosed with Glanzmann's thrombasthenia, who developed mucocutaneous, subconjunctival, and digestive hemorrhages, which was managed with tranexamic acid. The objective of this case report is to present the pathology and illustrate the appropriate diagnostic and therapeutic approach, as well as its main clinical manifestations.Item Aplasia cutis congénita tipo I en un recién nacido, reporte de caso(Universidad Santiago de Cali, 2023) Aluma López, María Alexandra; Kanan, Ahmad Talat (Director); Salcedo Libreros, Luis Felipe (Codirector)Aplasia cutis (ACC) is a congenital condition with an unusual appearance in pediatrics, especially in newborns, characterized by the absence of skin that can compromise the epidermis, dermis, and even underlying tissues such as the pericranium and meninges. ¹ A case report of a newborn clinically diagnosed with ACC is presented. According to Frieden's characteristics, it corresponds to the type 1 classification, taking into account the size and location of the lesion. The objective of this systematic review is to describe the aesthetic and functional results in a patient with ACC with conservative treatment.Item Hipertensión arterial secundaria a fibrodisplasia de la arteria renal izquierda en un paciente joven: reporte de caso(Universidad Santiago de Cali, 2024) Menjuren Tapie, Angie Catalina; Prado Jiménez, Joseph David; Moyano, Pablo Andrés (Director)Fibromuscular dysplasia (FMD) is a rare systemic vascular disease that primarily affects young women and accounts for 10% to 20% of all cases of renal artery stenosis worldwide. Renovascular hypertension accounts for 1% to 2% of all cases of hypertension in the general population, but plays a major role in treatable causes of hypertension in young people. Fibromuscular disease is thought to be a rare cause of renovascular hypertension and once diagnosed, patients may require angioplasty, but due to recurrence, long-term follow-up is necessary. (1) The aim of this paper is to present a clinical case of hypertension secondary to fibromuscular dysplasia of the renal artery in a young patient, reviewing the history, diagnostic methods and management in a hypertensive patient at an early age. The aim is to provide a comprehensive overview of this rare but significant condition. Furthermore, this case report serves as a research and educational tool for medical personnel, providing evidence that may be useful in future research and improving the understanding and management of fibromuscular dysplasia in clinical practice.Item Gangrena de Fournier en hombre: reporte de un caso(Universidad Santiago de Cali, 2024) Bravo Muñoz, Nicolle Dayhana; Manzano Jiménez, Sebastián; Valencia Betancourt, Rony Stiven; Romero Ortiz, Justy (Director)We present a 69-year-old male patient with a history of chronic kidney disease and type 2 diabetes mellitus, who was admitted to the Emergency Department and then to the ICU with a diagnosis of soft tissue sepsis secondary to Fournier's gangrene. The patient had presented with hemorrhoids for one month, but during the physical examination necrosis was evident in the perineum and anus, with clear signs of infection. Due to the severity of his condition, a colostomy and perineal debridement was performed on the same day of his admission. After this, the patient was admitted to the ICU, where he faced severe complications such as hemodynamic instability, acute respiratory failure, septic shock, and chronic renal failure. sharpened. Despite intensive treatment, including vasoactive support, mechanical ventilation, and renal replacement therapy, the patient's condition continued to deteriorate. He suffered cardiorespiratory arrest and was resuscitated, but his neurological condition worsened, and the family decided not to continue with resuscitative measures, which led to the patient's death. Hence the relevance of this clinical case, the complexity and severity of this pathology can be seen, underlining the importance of early and aggressive management in cases of Fournier's gangrene, as well as the ethical decisions involved in the management of high-risk cases. complexity.Item Meningitis aséptica asociada a parotiditis viral en paciente adulto inmunocompetente: reporte de caso y revisión de la literatura(Universidad Santiago de Cali, 2024) Astudillo Ponce, Nicolás; Vargas Gutiérrez, Anderson; Lozada Ramos, Heiler (Director)Aseptic meningitis due to the mumps virus is a rare complication. Although mumps is the most common clinical manifestation, the virus can cause serious complications such as meningitis, which in some cases can trigger severe neurological sequelae. This case report addresses an adult patient diagnosed with meningitis due to the mumps virus, describing the clinical presentation, the diagnostic and therapeutic approach, and emphasizing vaccination as a preventive measure. This case alerts us to the importance of rigorous clinical surveillance combined with early detection of meningeal complications in individuals with mumps. A timely intervention can reduce diagnosis time, thereby achieving adequate management and prompt detection of complications, having a positive impact by reducing costs and sequelae.
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