Medicina - Palmira

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    Relación entre el uso de esteroides anabólicos como factor predisponente para el desarrollo de hepatitis viral basada en una revisión bibliográfica
    (Universidad Santiago de Cali, 2025-05-06) Jaramillo Giraldo, Mariana; Jaramillo Mesa, Isabella; Santander Camacho, Zayira; Beitia, Pedro Nel
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    Modelos de comunicación para dar malas noticias en oncología y cuidados paliativos en pacientes adultos
    (Universidad Santiago de Cali, 2025-05-06) Castro Nieto, Richhard Emmanuel; Burbano Muñoz, Jelitza Johana; Moyano Pablo Andrés
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    Infecciones urinarias recurrentes como complicación en un paciente con síndrome de prune belly: reporte de caso
    (Universidad Santiago de Cali, 2025-05-06) Diana Marcela, Balanta Cordoba; Delgado Saavedra, Nelly Alexandra; Leal Naranjo, Sebastián; Molano Agudelo, Pedro Andrés; Talat Kanan, Ahmed
    Prune belly syndrome (PBS) is a rare congenital disorder characterized by bilateral cryptorchidism, abdominal muscle hypoplasia, and genitourinary anomalies. Its overall incidence is 1/30,000 live births, with a higher prevalence in males (3.8/100,000). In Colombia, its management is complex due to limited local documentation. Although its etiology is uncertain, it is associated with teratogenic and spontaneous factors. Urinary malformations, such as hydronephrosis and megabladder, predispose to recurrent urinary tract infections (UTIs). This study describes a pediatric case with recurrent UTIs as a complication of PBS and analyzes strategies to optimize its management.
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    Factores predisponentes y manejo preventivo en la gangrena de fournier mediante una revisión sistemática
    (Universidad Santiago de Cali, 2025-05-12) Gómez Enríquez, Mateo; campo franco, Jenny Fernanda; Pedro Nel Beitia
    Fournier's gangrene is a rare but potentially life-threatening, rapidly progressive necrotizing fasciitis that involves the soft tissues of the perineal, genital, and anorectal regions. It usually occurs in patients with risk factors related to diabetes mellitus, alcoholism, and obesity. The objective of this review is to identify and analyze risk factors and prevention strategies for Fournier's gangrene in the general population, with the goal of contributing to effective diagnosis and treatment. Materials and methods: For the creation of this review, an exhaustive search was conducted, selecting academic articles of high scientific recognition from 2020 to the present. Results: Identifying risk factors and preventing their potential complications are imperative for the early detection of Fournier's gangrene.
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    Análisis clínico, paraclínico y molecular en paciente pediátrica con mucopolisacaridosis iv-a en el suroccidente colombiano: reporte de caso
    (Universidad Santiago de Cali, 2025-05-08) Ardila Marín, Mariana; Caicedo Toro, Carlos Arturo; Rojas Banguero, Jeyson Steven; José María Satizabal Soto; Daniela Arturo Terranova
    Mucopolysaccharidosis type IV-A (MPS IV-A) is an autosomal recessive genetic disorder caused by a deficiency of the enzyme N-acetylgalactosamine-6-sulfatase, leading to the accumulation of chondroitin-6-sulfate (C6S) and keratan sulfate (KS). This disease has a low prevalence and is classified as a rare disease in Colombia under Resolution 023 of 2023. Furthermore, its incidence in Colombia appears to be higher than that reported in other countries worldwide. Genomic analysis of the GALNS gene has identified more than 400 variants in affected patients, enabling genotype–phenotype correlation studies. Mucopolysaccharidoses (MPS) are generally diagnosed late or misdiagnosed, resulting in delays in the initiation of enzyme replacement therapy and negatively affecting the development of complications that compromise patients’ quality of life.
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    Linfoma no hodgkin de células t maduras en estadio iv en un adulto medio con factor de riesgo exposicional y ambiental: reporte de caso
    (Universidad Santiago de Cali, 2025-05-08) Arcila Lenis, Maria Camila; Rendon Benavidez, Karen Liceth; Posso Holguin, Valentina; Cardona, María Alejandra
    Lymphomas are cancers that originate in the cells of the lymphatic system. It is important to note that the main types are Hodgkin lymphoma and non-Hodgkin lymphoma. Non-Hodgkin lymphoma can originate in lymphocytes, B cells, or T cells, with T-cell lymphoma being the rarest. We present the case of a 40-year-old male patient with no comorbidities and a history of exposure to environmental and exposure risk factors. The patient presented with skin lesions, which, after histopathological examination by biopsy, were diagnosed as stage IV mature T-cell non-Hodgkin lymphoma. Treatment was indicated with CHOEP-based chemotherapy, with an adequate clinical response. Environmental and exposure factors, diagnosis, and treatment of the disease in question are discussed.
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    Evidencia clínica y hemodinámica sobre el uso de azul de metileno en el manejo del shock: revisión de alcance de la literatura científica (2020-2025).
    (Universidad Santiago de Cali, 2025-05-08) Ramírez Mariaca, Marco Antonio; Juan José, Urrea Lasso; Vargas Quintero, Carlos Alfredo
    Shock, in its septic, vasodilatory, and distributive forms, represents a critical challenge due to its high mortality and the difficulty in maintaining adequate tissue perfusion. Methylene blue (MB), a modulator of the nitric oxide (NO) and guanylate cyclase (GC) pathways has emerged as an adjuvant therapy to counteract the refractory vasodilation associated with these conditions. Objective: To identify the characteristics of the current evidence to explore and synthesize indications for methylene blue in the treatment of shock, with emphasis on clinical, hemodynamic, and safety variables. Methodology: A scoping review of the literature was conducted using multiple clinical and cohort studies, systematic reviews, and databases such as PubMed, Nature, ScienceDirect, Scopus, and Web of Science. A reference matrix was used to collect information. Sixteen review articles were obtained.
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    Derrame pleural asociado a Sphingomonas paucimobilis: reporte de caso
    (Universidad Santiago de Cali, 2025-05-07) Luis Eduardo Moreno Henao; Bolaños Toro, Omar Fernando
    We discuss the case of a 91-year-old man with a history of hypertension, hypothyroidism, chronic kidney disease, and Alzheimer's dementia. The patient was admitted with a clinical picture of progressive dyspnea and pleural effusion with suspected pulmonary malignancy, in which Sphingomonas paucimobilis was documented. During hospitalization, he underwent antibiotic therapy, which led to clinical improvement and resolution of the effusions. However, there were indications suggesting a potential neoplastic condition. After discharge, he experienced recurrent respiratory problems, such as pneumothorax and new pleural effusions, in which the aforementioned organism was no longer documented. He ultimately died at home from an apparent pneumonia.
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    Estado del arte de la anticoncepción hormonal masculina: revisión sistemática
    (Universidad Santiago de Cali, 2023-11-24) Castaño Noguera, Lina Marcela; Canizales Trochez, Paula Andrea; Pérez López, Angie Daniela; Beitia Cardona, Pedro Nel
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    Presentación atípica de herpes zóster en una adolescente de 14 años.
    (Universidad Santiago de Cali, 2025-05-08) Ramos Vallejo, Juan Sebastián; Marín Restrepo, Isabella; Molano Agudelo, Pedro Andrés
    Herpes zoster (HZ) is a disease caused by the reactivation of the varicella-zoster virus (VZV), which remains latent in the dorsal root ganglia following a primary varicella (chickenpox) infection . The clinical course typically includes a prodromal phase characterized by general malaise and localized pain, followed by an eruptive phase with vesicular lesions distributed along a dermatome.This condition is rare in children under the age of 10 and occurs more frequently in immunocompromised individuals. Its incidence increases significantly in individuals over 50 years of age . We present the case of a fourteen-year-old immunocompetent adolescent who visited the emergency department with a clinical picture suggestive of herpes zoster, presenting in an atypical form with disseminated skin lesions and ophthalmic involvement. The only relevant medical history was maternal varicella infection during the third trimester of pregnancy.This case highlights the importance of considering herpes zoster in the differential diagnosis of skin rashes in adolescents, as early suspicion can lead to timely diagnosis, particularly in this age group where the condition has low incidence.
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    Panhipopituitarismo postraumático secundario a traumatismo craneoencefálico severo: reporte de caso.
    (Universidad Santiago de Cali, 2025-05-08) Vargas Solís, Juan Camilo; Motato Prado, Juan Sebastián; Arias Ramos, Deving
    Hypopituitarism is a clinical syndrome resulting from a deficiency in the secretion of one or more hormones produced by the anterior pituitary gland: thyroid-stimulating hormone (TSH), growth hormone (GH), prolactin, gonadotropins (LH and FSH), and adrenocorticotropic hormone (ACTH). We present the case of a 20-year-old female patient from Pradera, with a history of severe traumatic brain injury five years prior, who experienced a long-standing clinical course characterized by asthenia, adynamia, and amenorrhea, as well as episodes of dizziness, myalgia, a sensation of postural instability, facial, hand, and foot edema, bradypsychia, bradylalia, cold intolerance, chills, and drowsiness. Laboratory tests revealed low levels of anterior pituitary hormones. Brain magnetic resonance imaging (MRI) demonstrated an empty sella, leading to the diagnosis of hypopituitarism secondary to severe traumatic brain injury.
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    Carcinomatosis peritoneal de origen desconocido, estrategias diagnósticas y terapéuticas actuales: revisión sistemática de literatura
    (Universidad Santiago de Cali, 2025-05-12) Vega klusman, Erick; María Andrea, Cabal Arboleda; Romero Ortiz, Justy
    Peritoneal carcinomatosis with unknown primary tumor (PCUP) represents a significant diagnostic and therapeutic challenge, characterized by late presentation, uncertain origin, and unfavorable prognosis. Objective: To evaluate the impact of multidisciplinary diagnostic and therapeutic approaches on prognosis and quality of life in patients with PCUP. Method: A systematic review was conducted following PRISMA guidelines. Articles published between 2020 and 2025 in PubMed, Scopus, SciELO, and Web of Science were included. Inclusion criteria encompassed observational studies, clinical trials, systematic reviews, and case series with ≥30 patients. Evaluated parameters included: overall survival (OS), progression-free survival (PFS), quality of life (QoL), and complications (CTCAE v5.0).
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    Diagnóstico escalonado de fractura por sobrecarga en metáfisis proximal tibial: importancia del abordaje imagenológico multimodal. Reporte de caso y revisión de literatura
    (Universidad Santiago de Cali, 2025-05-08) Valencia Rivera, Dayana Gabriela; Mosquera, Brayan Ricardo
    This case report describes a progressive and systematic diagnostic process, based on clinical evaluation and imaging findings, for the diagnosis of a stress fracture in the proximal tibial metaphysis of a 28-year-old female military cadet and athlete. Case presentation: The case is characterized by a detailed correlation between clinical signs and the various imaging modalities used, including radiography, computed tomography, and magnetic resonance imaging, in association with persistent functional limitations, with the aim of comprehensively characterizing the underlying injury. This approach made it possible to accurately identify the nature and extent of the stress fracture, facilitating the development of an appropriate therapeutic plan.
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    Estadificación del síndrome de fragilidad mediante la escala de Fried en una población de adultos mayores institucionalizados de la ciudad de Palmira en el año 2025
    (Universidad Santiago de Cali, 2025-05-06) Cifuentes Pérez, Leidy Johana; Cuastumal Cuastumal, Jesus Andres; Pedraza Portela, Daniela; Molano Agudelo, Pedro Andrés
    To identify risk factors and stage frailty syndrome by applying the Fried scale to a population of institutionalized older adults in the city of Palmira in 2025, in order to provide recommendations for future public policies or intervention programs.
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    Métodos clínicos e imagenológicos para el diagnóstico de la Demencia Frontotemporal - Revisión de alcance (2021-2025)
    (Universidad Santiago de Cali, 2025-05-06) Agredo Escobar, Camilo; Panesso Colonia, Katie Fernanda; Quintero Vasquez, Paula Daniela; Mantilla Iza, Hernán David
    Frontotemporal dementia (FTD) is a neurodegenerative disorder that affects the frontal and temporal lobes, affecting personality, behavior, language, and other cognitive functions. It is the second most common dementia in people under 65 years of age and represents 5–10% of cases in those over 65 years of age. It is characterized by gradual progression and a wide variety of phenotypes such as behavioral (FTD-CV), progressive non-fluent aphasia (PPA-NF), and semantic aphasia (PPA-S). Structural imaging (CT and MRI) is helpful in the diagnosis but has limitations in early stages. Functional PET clearly detects metabolic dysfunctions before morphological changes. Despite advances, FTD remains underdiagnosed due to decreased consciousness and symptoms that are confused with psychiatric disorders.
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    Cigarrillo electrónico como una alternativa contra la adicción a la nicotina en fumadores crónicos. Revisión sistemática de literatura entre los años 2019 – 2025.
    (Universidad Santiago de Cali, 2025-05-07) Bravo Ramírez, Alejandro; Noguera Romero, Daniel Alejandro; Zamorano Saldarriaga, Felipe; Molano Agudelo, Pedro Andrés.
    The use of electronic cigarettes (ECs) is currently widespread among the general population, particularly among young people. Recently, their potential usefulness as an alternative for smoking cessation has been considered. The aim of this review is to determine the usefulness of electronic cigarettes by assessing the risk-benefit balance of their use as an alternative for nicotine cessation.
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    Neumonía recurrente en una paciente con esclerosis sistémica: reporte de caso
    (Universidad Santiago de Cali, 2023-10-26) López Corredor, Valentina; Mondragón Montano, Anderson Fabián.
    The clinical case of a 30-year-old female patient is presented, with a previous diagnosis of systemic sclerosis since 2022, who developed several episodes of pneumonia in the same year; Progressive systemic sclerosis or scleroderma is a rare chronic autoimmune disease that affects arterial microcirculation as well as the extracellular matrix, causing fibrosis in multiple tissues with organ dysfunction, especially at the lung level. The patient consulted due to an episode of dyspnea with the presence of tachypnea, hypoxemia, fatigue, paleness, rales at the lung bases, cachexia, microstomia, and presence of gastrostomy. The studies documented anemia, consolidative infiltrates especially in the right lower lobe, and positive blood culture for Staphylococcus Epidermidis. She received management with supplemental oxygen, antibiotic therapy, and corticosteroids, with gradual improvement, however with great deterioration in functional class.
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    Covid-19 y el síndrome inflamatorio multisistémico en paciente pediátrico
    (Universidad Santiago de Cali, 2023-10-19) Millan, Miguel Ángel; Arias Mitchell, Stanley Chipper; Barona Cabrera, Sebastian Francisco; Mondragón Montano, Anderson Fabián.
    COVID-19-associated multisystemic inflammatory syndrome in children is a potentially serious and rare condition, which needs better understanding to guide its management, consists of a cluster of symptoms related to swollen tissues and organs. It is currently related to Coronavirus 2019. The pathogenesis is unclear, but it has some features like Kawasaki syndrome, suggesting a vasculitis mechanism and a possible autoimmune etiology.
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    Determinantes del acto quirúrgico para prevenir ISO en adultos mayores hospitalizados 2018-2022: un protocolo de revisión de alcance.
    (Universidad Santiago de Cali, 2022-09-16) Lemos-Perlaza, Sebastian Augusto; Londoño Jiménez, Claudia Fernanda
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    Síndrome de Potter: factores de riesgo y tratamientos más comunes: revisión de alcance.
    (Universidad Santiago de Cali, 2023-10-26) Reyes Figueroa, Santiago; Echeverri Perea, Hugo Fernando; Rivera López, Juan Camilo; Salcedo Libreros, Luis Felipe
    Potter Syndrome is an orphan disease of very low prevalence, which is derived from oligohydramnios, generally due to kidney and urinary system malformations, which leads to lung hypoplasia and multiple abnormalities, highly reducing the life expectancy of the patient. neonate; The objective of this scoping review is to determine the associated risk factors and the most common treatments used in fetuses, neonates and pregnant mothers.