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Browsing Medicina by Subject "Alopecia"
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Item Evidencias, impacto y alternativas terapéuticas sobre alopecia inducida por quimioterapia: revisión de alcance(Universidad Santiago de Cali, 2024) Narváez Beltrán, Carlos Andrés; Vidal Cañas, Sinthia Michel; Liscano Martínez, Yamil (Director)Chemotherapy-induced alopecia is the abnormal loss of hair due to cytotoxic drugs in cancer treatment, it is one of the main adverse factors that affects the physical, emotional, and psychosocial state of the patient. Method: Scoping review, search of articles in databases Scopus, PubMed, Science Direct, Medline, Cochrane and clinicaltrials.gov, with the aim of demonstrating the effectiveness of pharmacological, physical, and alternative treatments, how they affect quality of life and in what cancer and regimen it is used. Results: Effectiveness in preventing AIC with scalp cooling (ECC) 58%, minoxidil 50%, topical Calcitriol 50%, CG428 Lotion 34.70%, Larrea divaricate lotion 613%, and effectiveness demonstrated qualitatively with low frequency ultrasound, no improvement is evident with the use of platelet-rich plasma; The effects on quality-of-life report evidence of reducing the need to purchase wigs and improvement in mood. AIC effectiveness in underlying breast cancers (69,5%) and solid cancers in treatments with anthracyclines and taxanes (79%). Conclusions: Effectiveness demonstrated with ECC and minoxidil not offered due to lack of knowledge and high costs, the alternatives still have little evidence to establish recommendations, little report on the effect on quality of life due to the lack of specific questionnaires; Alopecia is greater with anthracyclines and taxanes, hence the greater prevalence of alopecia in breast cancer. It recommends offering the treatments with the greatest evidence to patients at risk of AIC and designing studies in Colombia to provide results with a population focus