Química Farmacéutica
Permanent URI for this collection
Browse
Browsing Química Farmacéutica by Subject "Activated carbon"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Item Evaluación de la capacidad descontaminante IN-VITRO de las cáscaras de chontaduro en aguas contaminadas por ibuprofeno(Universidad Santiago de Cali, 2024) García Becerra, Betty Eliana; Urbano Montero, Marilyn; Ciro Monsalve, Yhors Alexander (Director)Currently, activated carbon is one of the most widely used adsorbent materials for environmental remediation purposes, especially for treating water contaminated with pharmaceuticals. In this regard, one of the main focuses is its production from renewable raw materials, such as residual plant matter, which in many cases is underutilized. In order to contribute to this approach, this study obtained activated carbon from peach palm (Bactris gasipaes) shells, a locally abundant waste product, through calcination using an acidic chemical agent (H3PO4 ) and a basic chemical agent (NaOH). Subsequently, the materials obtained were characterized through infrared spectroscopy, Boehm titration, and zero point of charge analysis. Furthermore, their in-vitro adsorption capacity for ibuprofen in aqueous solutions at neutral, acidic, and basic pH values was evaluated. The results obtained confirmed the successful production of activated carbon using both proposed methods, with more than 4000 mmol of surface functional groups per gram of material. Additionally, functional groups such as carboxylic acids, phenols, lactones, and amines were identified on the surface of the adsorbent materials. Finally, it was observed that these functional groups could be charged over a wide pH range, enhancing the removal of ibuprofen from aqueous media, reaching up to approximately 5 mg of ibuprofen per gram of activated carbon. This study highlights the potential of chontaduro shells as an alternative raw material for the production of adsorbent materials capable of removing ibuprofen from aqueous environments.Item Obtención de carbón activado a partir del desecho de cáscara de coco para la remoción in-vitro de fluconazol en aguas(Universidad Santiago de Cali, 2024) Coral Palacio, María Alexandra; Jara Sánchez, Laura Yineth; Ciro Monsalve, Yhors Alexander (Director)The increase of emerging contaminants in drinking water sources represents a significant challenge for public health and the environment. Among these contaminants, fluconazole, an antifungal drug widely used in clinical practice, has been identified as a problematic substance due to its persistence and potential negative impact on aquatic ecosystems. In response to this issue, the use of activated carbons derived from renewable sources has emerged as a promising alternative, with the potential for efficient adsorption of pharmaceutical compounds in aqueous solutions. In this way, adsorbent materials were developed from coconut shell waste by chemical treatment with CaCl2 and H3PO4, the presence of functional groups in their structures was evaluated by the Boehm method, and its adsorption capacity of fluconazole was evaluated at different doses of the drug (6 and 10 ppm), amount of adsorbent material (20 and 50 mg), pH (3.0 and 7.0) and ionic strength (0.5, 1.0 and 1.5 M). Activation with CaCl2 and H3PO4 yielded 10.17% and 16.3% respectively. Boehm titration revealed carboxylic, phenolic, and lactonic functional groups, critical to the fluconazole adsorption process