Medicina - Palmira
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Browsing Medicina - Palmira by Author "Arana Domínguez, Johan Daniel (Director)"
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Item Ecthyma gangrenosum of fungal origin: case report(Universidad Santiago de Cali, 2023) León Sánchez, Germán Andrés; Arana Domínguez, Johan Daniel (Director); Lozada Ramos, Heiler (Codirector)Item Endocarditis por Streptococcus equi spp: reporte de caso(Universidad Santiago de Cali, 2023) Imbacuan Moreno, Daniel Camilo; Villacorte Sánchez, Royman Gustavo; Quiceno Pulido, Mayerli Johana; Arana Domínguez, Johan Daniel (Director); Lozada Ramos, Heiler (Codirector)The present case report and literature review support that, although severe human infections with Streptococcus equi spp are rare, they have a poor prognosis and lead to high patient morbidity and mortality; cases have been documented mainly in patients with close contact with animals, especially horses, and with consumption of unpasteurized dairy products. Worldwide, gram-positive bacteria account for approximately 80% of cases of native valve infective endocarditis (IE). These bacteria include Staphylococcus aureus in 35 to 40% of native IE cases, streptococci in 30 to 40% (Streptococcus viridans in approximately 20%, Streptococcus gallolyticus [formerly S. bovis] and other streptococci in approximately 15%, within this percentage streptococcus equi is included), and enterococci in 10% [2]. We present the case of a patient with infective endocarditis due to streptococcus equi spp, from which we will describe the clinical, microbiological and imaging diagnostic approach that are useful, as well as the current therapeutic approach for the management of infective endocarditis due to this germ.Item Fagoterapia: una nueva alternativa terapéutica en la resistencia a los antibióticos - revisión sistemática(Universidad Santiago de Cali, 2023) Osorio Hernández, Sofía; Perea Gordillo, Laura Sofía; Arana Domínguez, Johan Daniel (Director); Molano Agudelo, Pedro (Codirector)Discovered in 1917, bacteriophages are viruses that parasitize and lyse bacteria, releasing new phages and forming the basis of phage therapy, a non-antibiotic medical technique being investigated as an alternative to combat growing global antimicrobial resistance. Given this global challenge, a systematic review (following the PRISMA 2020 guidelines) was conducted in databases like Scopus and PubMed, including 28 articles published between 2017 and 2023. The collected evidence showed that Europe leads the research on phage therapy aimed at antibiotic resistance, highlighting its advantages such as high specificity, low cost, and low rate of side effects, along with its ability to control infections. However, phage therapy faces significant limitations hindering its widespread clinical use, including the lack of extensive studies to understand phages' genome and properties, the absence of a standard regulatory framework, and the complexity of selecting the correct bacteriophage for a specific bacterial infection.Item Perfil socioeconómico de los estudiantes admitidos al programa de medicina de la Universidad Santiago de Cali durante el período académico 2022-A y 2022-B(Universidad Santiago de Cali, 2023) González Parra, Alejandra; Rivas Delbasto, Valentina; Rojas Gutiérrez, Daniela; Arana Domínguez, Johan Daniel (Director)Item Riesgos, beneficios e indicaciones del cannabis en el tratamiento del Parkinson, revisión sistemática(Universidad Santiago de Cali, 2023) Rincón Valencia, Daniela; Arroyave Muñoz, Daniela; Cobo Restrepo, Silvana; Arana Domínguez, Johan Daniel (Director)Parkinson's Disease (PD) is a neurodegenerative disorder with motor and non-motor manifestations, whose pathological process begins years before clinical symptoms, and medicinal cannabis has been investigated as a therapeutic option that acts as a neuromodulator and neuroprotector by influencing cannabinoid receptors (CB1R and CB2R). Through a systematic review of freely available articles published between 2015 and 2022, the study aimed to describe the benefits, risks, and indications of using cannabis for Parkinson's treatment to update therapies and improve patients' quality of life. The results indicate that a significant proportion of PD disability is attributable to motor complications and levodopa-insensitive symptoms, and while there has been an increase in therapeutic options for these complications, many are unavailable in our country or fail to meet all of the patients' individual clinical needs.Item Síndrome de activación macrofagocítica en un paciente pediátrico. Reporte de caso(Universidad Santiago de Cali, 2023) Arias Eusse, María Camila; Basto Domínguez, Carolina; Montoya Hurtado, Carolina; Arana Domínguez, Johan Daniel (Director)Hemophagocytic syndrome (SHF), also known as hemophagocytic lymphohistiocytosis (HLH), usually occurs mainly in childhood being a serious disease resulting from a deregulation of the immune system either by infectious causes, neoplastic, genetic, metabolic or rheumatological leading to an exaggerated immune response. This syndrome acts quickly and puts the patient’s life at risk, so the diagnosis must be based on clinical and paraclinical criteria and then HLH-2004 protocol must be initiated. This case report will be important to make this pathology visible since it is uncommon, which occurs in all age groups, but mainly in pediatric age, has an incidence of 1 in 50,000 live births and varies by geographical region (1). We present the case of a minor patient with a diagnosis of Hemophagocytic Syndrome in whom paraclinics and diagnostic images are taken, biopsy and bone marrow aspirate plus study of the Cerebrospinal Fluid.