Cryptococcal Meningitis in an HCV-Positive and IVDU-and HIV-Negative Patient: A Case Report and Literature Review

Simple item page
dc.contributor.authorLozada Ramos, Heiler
dc.contributor.authorÁlvarez Payares, Jorge
dc.contributor.authorDaza Arana, Jorge Enrique
dc.contributor.authorSalas Marín, Luisa María
dc.date.accessioned2025-07-10T22:04:24Z
dc.date.available2025-07-10T22:04:24Z
dc.date.issued2024
dc.description.abstractBackground: Cryptococcal meningitis (CM) is a central nervous system (CNS) infection that occurs mainly in immunocompromised individuals such as those with human immunodeficiency virus (HIV) infection. However, the prevalence of CM in immunocompetent patients has increased. Although CM has been reported in patients with hepatitis C virus (HCV) infection, it has not yet been fully established whether there is an association between both conditions. CM has also been reported in patients with intravenous drug use (IVDU), which is related to the immunosuppression caused by these drugs. Case Presentation: We report the case of a 24-year-old man who presented with meningitis secondary to Cryptococcus gattii infection. He had a history of IVDU and HCV infection, was HIV-negative and without antiviral treatment. The patient received adequate antifungal treatment during induction, consolidation, and maintenance phases. His condition relapsed, requiring dose adjustment, with an excellent response during clinical follow-up for both meningitis and HCV infection. A brain biopsy was requested during relapse to rule out other co-infection. Conclusion: The case of an individual diagnosed with cryptococcal meningitis, who had a history of IVDU and HCV infection, is presented. The coexistence of such events could shadow the prognosis of this group of subjects, related to immunosuppression that can be caused through different pathways. Having HCV and being a IVDU simultaneously could increase the risk of Cryptococcus infection.
dc.identifier.citationozada-Ramos H, Álvarez-Payares J, Daza-Arana JE, Salas-Marín LM. Cryptococcal Meningitis in an HCV-Positive and IVDU- and HIV-Negative Patient: A Case Report and Literature Review. Int Med Case Rep J. 2024;17:855-860 https://doi.org/10.2147/IMCRJ.S486119
dc.identifier.issn1179142X
dc.identifier.urihttps://repositorio.usc.edu.co/handle/20.500.12421/7384
dc.language.isoen
dc.publisherDove Medical Press Ltd
dc.subjectcryptococcal meningitis
dc.subjectcryptococcosis
dc.subjecthepatitis C
dc.subjectHIV infection
dc.subjectintravenous drug use
dc.titleCryptococcal Meningitis in an HCV-Positive and IVDU-and HIV-Negative Patient: A Case Report and Literature Review
dc.typeArticle

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Cryptococcal Meningitis in an HCV-Positive and IVDU-and HIV-Negative Patient.pdf
Size:
1.57 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Científicos

Higher Education Institution subject to inspection and surveillance by the Ministry of National Education.
Legal status granted by the Ministry of Justice through Resolution No. 2,800 of September 2, 1959.
Recognized as a University by Decree No. 1297 of 1964 issued by the Ministry of National Education.

Institutionally Accredited in High Quality through Resolution No. 018144 of September 27, 2021, issued by the Ministry of National Education.

Ciudadela Pampalinda

Calle 5 # 62-00 Barrio Pampalinda
PBX: +57 (602) 518 3000
Santiago de Cali, Valle del Cauca
Colombia

Headquarters Centro

Carrera 8 # 8-17 Barrio Santa Rosa
PBX: +57 (602) 518 3000
Santiago de Cali, Valle del Cauca
Colombia

Palmira Section

Carrera 29 # 38-47 Barrio Alfonso López
PBX: +57 (602) 284 4006
Palmira, Valle del Cauca
Colombia

DSpace software copyright © 2002-2025 LYRASIS


Hosting & Support