Fast and selective synthesis of mono-substituted sucrose methacrylate ester monomer

Abstract

Sucrose methacrylate (SM) is a key monomer for synthesizing biocompatible polymers with a carbohydrate core. However, controlled SM synthesis is challenging due to the possible formation of regio-isomers. This study describes SM synthesis that involves ultrasound irradiation of a homogeneous basic medium. The selectivity for mono-substituted SM was 86% within 30 min of reaction. The newly developed methodology is faster and more selective than that of mono-substituted SM synthesis already described in the literature.

Description

Keywords

Methacrylate, Monomer, Sucrose ester, Ultrasound

Citation

Rojas Sterling, J. C., Ortega, J. O., Metzker, G., Boscolo, M., & Mora Vargas, J. A. (2022). Fast and selective synthesis of mono-substituted sucrose methacrylate ester monomer. Carbohydrate Research, 511. https://doi.org/10.1016/j.carres.2021.108465