Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia
| dc.contributor.author | Rada, Ana Mercedes | |
| dc.contributor.author | Correa, Adriana | |
| dc.contributor.author | Restrepo, Eliana | |
| dc.contributor.author | Capataz, Cesar | |
| dc.date.accessioned | 2025-07-04T15:52:43Z | |
| dc.date.available | 2025-07-04T15:52:43Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | An Escherichia coli isolate sequence-Type 471 (ST471) producing Verona integron-encoded metallo-β-lactamases (VIM)-4 was recovered from a rectal swab in a patient without travel records with osteomyelitis in Colombia. The isolate carried a class 1 integron-borne blaVIM-4 gene with a 170-bp duplication in the 3′ end of the gene, preceded by an aac(6′)-Ib gene. The genetic environment of blaVIM-4, blaCMY-2, and sul2 genes showed similarities to the backbone of pKKp4, an IncA/C-Type plasmid from a Klebsiella pneumoniae strain carrying blaVIM-4 recovered in Kuwait. This is the first report of blaVIM-4 in Enterobacterales in South America. Our results suggest that blaVIM-4 gene was found on an IncA/C-Type plasmid that could play a role in the spread of VIM-4 carbapenemase in Colombia. | |
| dc.identifier.citation | Rada, A. M., Correa, A., Restrepo, E., & Capataz, C. (2022). Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia. Microbial Drug Resistance, 28(3). https://doi.org/10.1089/mdr.2021.0031 | |
| dc.identifier.issn | 10766294 | |
| dc.identifier.uri | https://repositorio.usc.edu.co/handle/20.500.12421/7169 | |
| dc.language.iso | en | |
| dc.publisher | Mary Ann Liebert Inc. | |
| dc.subject | BlaVIM-4 | |
| dc.subject | Colonization | |
| dc.subject | Escherichia coli | |
| dc.subject | Metallo-β-lactamase | |
| dc.title | Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia | |
| dc.type | Article |
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