Browsing by Author "Carabali Arboleda, Antony"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Obtención de perseitol a partir de las semillas de Persea americana y evaluación de su actividad antimicrobiana en emulsiones cosméticas(Universidad Santiago de Cali, 2025) Carabali Arboleda, Antony; Suarez Osorio, LisethPerseitol (D-glycero-D-galacto-heptitol) is a seven-carbon monosaccharide polyol, an alditol of interest in the plant kingdom, and an essential compound that can be recovered from agroindustrial waste. This study focused on the extraction of metabolites from Persea americana seeds, with the aim of deciding the presence of reducing sugars, evaluating their antimicrobial activity, and exploring their potential application in cosmetic formulations. To this end, Persea americana seeds were subjected to ultrasound-assisted methanolic extraction. The resulting crude extract was characterized by using the Fehling test for the detection of reducing sugars, and its antimicrobial activity against Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923 strains were evaluated. The extract was incorporated into a water-in-oil (W/O) emulsion to assess its physicochemical stability. A crude extract was obtained with a 34% yield (w/w). The Fehling test showed positive results for the presence of reducing sugars, consistent with the known composition of avocado seeds, including D-mannoheptulose. However, the extract did not show significant antimicrobial activity against E. coli or S. aureus under the conditions evaluated. The emulsion formulated with the extract achieved a yield of 80.46%. Physicochemical stability assessments (pH and viscosity) of the emulsions stored at room temperature (22 ± 1 °C) and refrigerated (3 °C) showed good stability throughout the study period. Despite the absence of antimicrobial activity under the conditions evaluated, the detection of reducing sugars in the methanolic extract suggests its potential as a humectant in cosmetic applications, given the water-binding ability of these compounds. Therefore, further characterization and purification of perseitol and other bioactive metabolites from Persea americana seeds call for further investigation for future applications