Doctorado en Ciencias Aplicadas
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Browsing Doctorado en Ciencias Aplicadas by Author "Zambrano Bermeo, Rosa Nury (Directora)"
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Item Relación del flujo sanguíneo y la temperatura en función del tiempo con la hiperemia reactiva como indicador temprano de lesiones por presión(Universidad Santiago de Cali, 2025-11-14) Jiménez Cerquera, Catalina ; Zambrano Bermeo, Rosa Nury (Directora); Manrique Julio, Jorge Eliecer (Director)To analyze the time course of skin blood flow and temperature, using reactive hyperemia as an early indicator of pressure injuries in older adults. Methods. We conducted a prospective observational cohort study (n = 55). Descriptive statistics and normality tests were applied; bivariate analyses explored the association and/or significance of other variables with the occurrence of a hyperemic response. The hyperemic response (BF_max) was modeled using discrete-time survival with a complementary log–log (cloglog) link and a log offset. Additionally, a robust logistic/GEE model was fitted including optical–structural determinants (Red/IR ratio, thickness). We constructed a Cutaneous Microvascular Response Index, composed of responsiveness (how fast and how much flow increases) and recovery capacity (ability to return to baseline). Model performance (AUC, Brier score) and associations (OR/HR with 95% CI) were assessed. Results. We characterized the temporal behavior of blood flow and temperature at the evaluated site up to the onset of the hyperemic response, identified its latency and conditions of occurrence, and proposed a model that not only represents the data dynamics but also shows potential utility to stratify cutaneous microvascular risk and complement clinical scales such as Braden.