Medicina - Palmira

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Riesgos, beneficios e indicaciones del cannabis en el tratamiento del Parkinson, revisión sistemática
(Universidad Santiago de Cali, 2023) Rincón Valencia, Daniela; Arroyave Muñoz, Daniela; Cobo Restrepo, Silvana; Arana Domínguez, Johan Daniel (Director)
Parkinson's Disease (PD) is a neurodegenerative disorder with motor and non-motor manifestations, whose pathological process begins years before clinical symptoms, and medicinal cannabis has been investigated as a therapeutic option that acts as a neuromodulator and neuroprotector by influencing cannabinoid receptors (CB1R and CB2R). Through a systematic review of freely available articles published between 2015 and 2022, the study aimed to describe the benefits, risks, and indications of using cannabis for Parkinson's treatment to update therapies and improve patients' quality of life. The results indicate that a significant proportion of PD disability is attributable to motor complications and levodopa-insensitive symptoms, and while there has been an increase in therapeutic options for these complications, many are unavailable in our country or fail to meet all of the patients' individual clinical needs.