Medicina - Palmira

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Úlcera arterial crónica en paciente con poliautoinmunidad, reporte de caso
(Universidad Santiago de Cali, 2024) Arboleda Rúales, Angie Daniela; Quintero Narváez, Laura Isabella; Ortiz Guzmán, Xiomara Katherin; Mondragón Montaño, Anderson Fabian (Director)
A case of an elderly patient with a chronic arterial ulcer attributed to scleroderma (SS) is presented; however, multiple systemic alterations explained by a phenomenon of polyautoimmunity are evident. In this condition, various and complex alterations of immunity are combined that generate clinical syndromes that are difficult to interpret, causing confusion and delays in diagnosis and management. This patient, treated at a level I hospital and with a history of Hansen disease, exhibits initial mucocutaneous involvement and later hematological, pulmonary, and autoimmune findings that suggest a systemic disease that is difficult to differentiate between SSc and Systemic Lupus Erythematosus (SLE). This generated delays in the start of immunosuppressive pharmacological treatment and great disability in the patient, as well as prolonged hospitalization stays. Flaws are evident in the comprehensive approach to patients with an autoimmune condition and access barriers to specialized care in highly complex institutions. This report attempts to ratify the theory about the presence of polyautoimmunity in a significant proportion of patients with scleroderma in the Afro-Latino population.