Browsing by Author "Varela, Liddy"
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Item Factors associated with unsuccessful treatment outcome for tuberculosis in previously treated patients in Cali, Colombia, during the period 2015-2019(Instituto Nacional de Salud, 2023-09-30) Varela, Liddy; Ortiz, Jimena; García, Pamela K.; Luna, Lucy; Fuertes Bucheli, José F.; Pacheco, RobinsonIntroduction. Tuberculosis treatment success rates remain suboptimal.Objective. To identify factors associated with unsuccessful treatment for tuberculosis in patients with a history of tuberculosis treatment.Materials and Methods. A retrospective, analytical, observational cohort study of patients readmitted to a mycobacterial program in Cali, Colombia, was conducted. Patients older than 15 years with pulmonary tuberculosis between 2015 and 2019 with a history of tuberculosis treatment were included. Patients with resistant tuberculosis were excluded.Results. Six hundred and fifty-five patients with treatment history were admitted, 60 % for inconclusive treatment and 40 % for relapse. Compared to patients readmitted for relapse (ORa= 2.34; CI=1.62-3.38), the variables that independently explained unsuccessful tuberculosis treatment at discharge were: being homeless (ORa=2.45; CI=1.54-3.89), being drug dependent (ORa=1.95; CI=1.24-3.05), having TB/HIV coinfection (ORa=1.69; CI=1.00-2.86) or diabetes (ORa=1.89; CI=1.29-2.77), and failure to comply with previous treatment due to loss to follow-up, dropout or other causes. Programmatic variables that favored treatment success were voluntary HIV test counseling (p < 0.001) and HIV test performance (p < 0.001).