Browsing by Author "Taborda Valencia, Jazmin"
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Item Infecciones por Vibrio vulnificus en individuos inmunocomprometidos. Revisión sistemática(Universidad Santiago de Cali, 2025-12-01) Taborda Valencia, Jazmin; Duque Zapata, Juan Diego (Director)Vibrio vulnificus is a gram-negative, halophilic and thermophilic bacterium, present in warm coastal and estuarine waters, it is known to cause serious infections such as necrotizing fasciitis and sepsis. These infections attack people with weakened immune systems, especially those with chronic liver disease, diabetes, alcohol problems and old age. The contagion occurs by eating contaminated raw seafood, especially oysters, or by the exposure of open wounds in salt water. The most serious cases have ended in amputations or death, with a mortality rate that exceeds 50% among the most exposed people. The study aimed to analyze which factors increase the risk of developing necrosis and sepsis in immunocompromised people infected with V. vulnificus. A review was carried out, following the PRISMA methodology, looking for information in databases such as Science Direct and Scopus, considering articles published between 2015 and 2024. Boolean criteria and tools such as Rayyan and Zotero were used to organize and choose the most relevant information. The results showed that certain pre-existing conditions, such as liver disease, blood problems and immune deficiencies, significantly increase the vulnerability and severity of the infection. In addition, it was observed that these associated diseases accelerate the advance towards septicemia and septic shock. In conclusion, it was determined that the identification of risk factors in immunocompromised patients is essential to improve prevention strategies and medical treatment of Vibrio vulnificus infections.