Browsing by Author "Ruiz Jiménez, Paola Andrea"
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Item Autoimmune Hemolytic Anemia Caused by Cold Agglutinin Antibodies in Systemic Lupus erythematosus—a Rare Association: Case Report(Dove Medical Press Ltd, 2023-09-04) Osorio Toro, Luis Miguel; Quintana Ospina, Jhon Herney; Melo Burbano, Luis Álvaro; Ruiz Jiménez, Paola Andrea; Daza Arana, Jorge Enrique; Rivas Tafurt, Giovanna Patricia; Izquierdo Loaiza, Jorge HernánAutoimmune hemolytic anemias (AIHAs) are rare and heterogeneous disorders characterized by the destruction of redblood cells by warm or cold antibodies. Hemolytic anemia associated with warm antibodies is the most common, whereas coldantibodies are rare and infrequent in cases published in the scientific literature. Herein, we present the case of a young patient withsystemic lupus erythematosus (SLE) and autoimmune hemolytic anemia caused by cold antibodies. Initially, infectious etiology andhematological malignancy were considered, which were ruled out. She required management in the intensive care unit due to severehematological involvement and responded well to immunomodulatory therapy. This case illustrates the importance of a strong clinicalsuspicion of AIHA due to cold agglutinins associated with SLE when faced with similar clinical symptoms in order to achieve a timelydiagnosis and provide optimal therapy.