Browsing by Author "Rosales Jimenez, Ligia Nicole"
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Item Relación entre la disbiosis intestinal y el desarrollo de las alergias alimentarias en perros, revisión sistemática(Universidad Santiago de Cali, 2025) Rosales Jimenez, Ligia Nicole; Correa Toro, Nelson William (Director)The canine gut microbiome is a complex ecosystem that plays essential roles in digestion, metabolism, and immune regulation. Under eubiosis, the main bacterial phyla contribute to homeostasis by producing short-chain fatty acids (SCFAs), which strengthen the epithelial barrier and promote the induction of regulatory T lymphocytes. However, factors such as antibiotic use, ultra-processed diets, and aging favor dysbiosis, characterized by a loss of microbial diversity, altered proportions of key taxa, and an increase in pro-inflammatory bacteria. These changes are associated with the development of food allergies, mediated by exacerbated Th2 responses and inadequate IgA production. Recent studies show that diet, mode of delivery, and early microbial exposure significantly influence immune system maturation, supporting the hygiene hypothesis. Targeted therapies, such as fecal microbiota transplantation, probiotics, and postbiotics, aim to restore the microbiota and induce immune tolerance. Understanding the interaction between microbiota and immunity allows for the development of preventative and therapeutic strategies to improve intestinal health and well-being in dogs.