Browsing by Author "Murillo Betancur, Camila"
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Item Análisis de los diferentes recubrimientos antimicrobianos innovadores, para la prevención de infecciones en implantes óseos. Revisión bibliográfica(2024) Sánchez Moncayo, Angie Bridgeth; Murillo Betancur, Camila; López López, María NelaIntroduction: Considering bone abnormalities due to trauma or genetics, it has been necessary to innovate with new ways to improve prostheses and orthopedic implants, adding antimicrobial characteristics to prevent implant-associated infections (IAI). Objective: To analyze the different types of innovative antimicrobial coatings for the prevention of infections in bone implants. Materials and methods: A bibliographic review of antimicrobial coatings in bone implants was performed. Information was collected in a tracking matrix, in various languages, including English and Portuguese. 57 articles were reviewed, of which 44 were selected, from databases such as Science Direct, PubMed and Web of Science. Results: Materials such as magnesium, nanostructured silver, antibiotics and titanium nitride were compared, each with antimicrobial properties and specific characteristics that make them suitable for different surgical contexts. Magnesium demonstrated an excellent method of action for corrosion avoiding bacterial biofilm creations. Antibiotics: Of 315 patients treated, only six patients had deep preprosthetic infection or osteomyelitis, which were treated with oral or intravenous drugs, two patients required nail replacement. Nanostructured silver excelled in areas of high risk of infection and low mechanical load, while titanium nitride was ideal in areas of greater load. The results underline the importance of customizing coatings according to patient needs and type of intervention, in addition to highlighting the potential of non-antibiotic antimicrobial alternatives to combat bacterial resistance. Conclusion: We conclude that antimicrobial coatings represent a promising way to reduce postoperative complications and prolong implant life, however, additional clinical studies are recommended to confirm their long-term safety and efficacy, consolidating their application in orthopedic and reconstructive surgical environments