Browsing by Author "Moreno Vivas, Valentina"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Obtención de péptidos con potencial farmacológico a partir de hidrolisis enzimática in silico de la proteína de quinua con pepsina(Universidad Santiago de Cali, 2024) Moreno Vivas, Valentina; García León, Nathaly; Oñate Garzón, José Fernando (Director); Liscano Martínez, Yamil (Director)Peptides are protein fragments, whose amino acid sequence determines their structure and function, they have various biological functions and have antimicrobial, anticancer, antioxidant, anti-inflammatory activities, among others. They are obtained through enzymatic or acid hydrolysis processes that catalyze the breaking of peptide bonds, thus obtaining bioactive peptides used in various industries due to their ability to selectively interact with other molecules, being of interest in medical research for the development of new therapies. and diagnoses. Quinoa is a rich source of peptides that contain bioactive compounds beneficial for health. Performing peptide synthesis with enzymatic hydrolysis in vitro can be complex and expensive, requiring precision in the union of amino acids and with low yields. Cheaper alternatives, such as in silico enzymatic hydrolysis, have been developed using bioinformatics tools to predict bioactive peptides. In some studies, the pharmacological potential of peptides obtained from quinoa by in silico enzymatic hydrolysis has been evaluated. This approach could significantly impact the pharmaceutical industry, facilitating the development of new drugs for chronic diseases and improving quality of life. This implies an advance in scientific and technological knowledge, especially in the pharmaceutical industry.