Browsing by Author "Lemos Bedoya, Mayerlin"
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Item Detección de plásmidos conjugativos en aislados de Escherichia coli resistentes a beta-lactámicos provenientes de la ciudad de Cusco, Perú(Universidad Santiago de Cali, 2023) Lemos Bedoya, Mayerlin; Pantoja Ibarra, Sergio Esteban; Del Carmen Falco Restrepo, Aura Dayana; Correa Bermudez, AdrianaEscherichia coli is the most common uropathogen causing Urinary Tract Infections (UTI) in the community worldwide. Which makes it an opportune candidate for the dissemination of resistance genes at the hospital level. In recent years in Latin America, there has been an increase in ESBL-producing E.coli strains, especially in countries such as Peru, where rates of resistance to beta-lactams by ESBL-producing E.coli strains have been recorded close to the 20%. However, despite this, few epidemiological data are available and no study is known in which the presence of conjugative plasmids is directly related to resistance to beta-lactams present in the isolates. Therefore, in this study conjugative plasmids were detected in E. coli isolates from the city of Cusco, Peru. With this, the presence of plasmids will be identified in 81% of the strains evaluated and, in addition, it will be verified that 100% of the isolates have the capacity to transfer extrachromosomal information during the conjugation process. With this information, it was concluded that the three hospitals evaluated (Regional Hospital of Cusco, EsSalud and Hospital Antonio Lorena) located in the city of Cusco, are a possible reservoir of E. coli strains carrying conjugative plasmids that sustained resistance to the beta-lactam antibiotics. For this reason, the implementation of the guidelines suggested by the WHO in 2016 is recommended, in order to reduce the prevalence of multi-resistant strains at the hospital level