Browsing by Author "Gutierrez, Gustavo"
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Item A Photochemical and Electrochemical Triggered Bis(hydrazone) Switch(Chemistry - A European Journal, 2017) Gordillo, Mónica A.; Soto-Monsalve, Mónica; Carmona-Vargas, Christian C.; Gutierrez, Gustavo; D'vries, Richard F.; Lehn, Jean-Marie; Chaur, Manuel N.Herein, we report the synthesis of a double hydrazone capable of undergoing photochemical E/Z isomerization through the imine double bonds. The bis(hydrazone) 1-E,E can be considered as a ""two-arm"" system in which the controlled movement of each arm is obtained by photo-modulation, making possible the appearance of two isolable metastable isomeric states 1-E,Z and 1-Z,Z. Such states are characterized by very specific structural, optical and electrochemical properties. The latter, allows the reversible return from either 1-E,Z or 1-Z,Z to the 1-E,E state. Our results are of great importance in the further development of molecular machines and photochemically controlled reactions by introducing for the first time double hydrazones as tunable photochemical switches.Item Spergulagenic Acid A: Isolation and single crystal structure elucidation(Elsevier B.V., 2019-07-19) Montoya, Guillermo; Gutierrez, Gustavo; D'Vries, Richard; Ellena, Javier; Panay, Aram J.In the present work, the crystal structure of (3b)-3-acetoxy-30-methoxy-30-oxo-olean-12-en-28-oic acid, (Spergulagenic Acid A) is presented. The compound was isolated from Cecropia telenitida roots, employing semi-pilot scale extraction system and automated flash chromatography device. Vapor diffusion of methanol in chloroform yield suitable crystals for X-ray diffraction. The crystal packing of the Spergulagenic Acid A as methanol solvate is formed by strong hydrogen bonds between the SA-A molecule and the methanol. SA-A as well other pentacyclic triterpenes, present interesting potential biological activities. Inasmuch as biological activity is clearly related to molecular structure, the main goal of the present work was the structural elucidation of this molecule by single crystal X-ray diffraction. To the best of our knowledge, there is no previous crystal structure report in the literature for the titled compound or any other with simultaneous substitution at C2 and C7.