Browsing by Author "Granja Banguera, Claudia Patricia"
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Item A Facile Glycerol-Assisted Synthesis of Low-Cu2+-Doped CoFe2O4 for Electrochemical Sensing of Acetaminophen(2023-11) Alfonso González, José Guillermo; Granja Banguera, Claudia Patricia; Morales Morales, Jimmy Alexander; Dector, AndrésThis work devised a simple glycerol-assisted synthesis of a low-Cu2+-doped CoFe2O4 and the electrochemical detection of acetaminophen (AC). During the synthesis, several polyalcohols were tested, indicating the efficiency of glycerin as a cosolvent, aiding in the creation of electrode-modifier nanomaterials. A duration of standing time (eight hours) before calcination produces a decrease in the secondary phase of hematite. The synthesized material was used as an electrode material in the detection of AC. In acidic conditions (pH 2.5), the limit of detection (LOD) was 99.4 nM, while the limit of quantification (LOQ) was found to be (331 nM). The relative standard deviation (RSD), 3.31%,was computed. The enhanced electrocatalytic activity of a low-Cu2+-doped CoFe2O4-modified electrode Cu0.13Co0.87Fe2O4/GCE corresponds extremely well with its resistance Rct, which was determined using the electrochemical impedance spectroscopy (EIS) technique and defined its electron transfer capacity. The possibility of a low-Cu2+-doped CoFe2O4 for the electrochemical sensing of AC in humanurine samples was studied. The recovery rates ranging from 96.5 to 101.0% were obtained. These findings suggested that the Cu0.13Co0.87Fe2O4/GCE sensor has outstanding practicability and could be utilized to detect AC content in real complex biological samples.Item Coprecipitación de hidrotalcitas y aplicación de sus óxidos en la síntesis de bases de Schiff derivadas de 2-aminotiazol y aldehídos aromáticos(Universidad Santiago de Cali, 2021) Granja Banguera, Claudia Patricia; Morales Morales, Jimmy Alexander (Director); Mora Vargas, Jorge Andrés (Codirector)Recently, the development of new methodologies for the synthesis of products with value-added has increased, especially, the obtaining of compounds that present in their structure sulfur and nitrogen atoms mainly in heterocyclic rings, and that also contain other types of functional groups. For example, imine group (-C=N-), because they are of great importance for their applications as anticancer, antibacterial, antifungal, antiinflammatory agents, among others. Herein, we the synthesis of 1-phenyl-N-(thiazol-2-yl)methanimine (Schiff's base, SB) derived from 2-aminothiazole and benzaldehyde using mixed metal oxides (MMOs) derived from hydrotalcites (LDHs) modified with Ni2+ and Cu2+. The LDHs were synthesized by coprecipitation method, and their subsequent thermal treatment provided the corresponding MMOs. MMOs were investigated for imines synthesis in solvent free and microwave-assisted conditions. The physicochemical characterization of the LDHs demonstrated the insertion of Ni2+ and Cu2+ ions in the lamellar structure and no secondary phase formation was observed. XRD of the MMOs obtained showed the decrease in the crystallinity of the precursor and the formation of three characteristic peaks of this type of oxides, proving they are obtaining. SB was obtained with 51.3% yield when the MMO modified with 15% Cu2+ as catalyst and 1.0 equivalent of each of the starting reagents was used in 10 min of reaction at 300 W and 125 ° C.