Browsing by Author "Cantor Pareja, Stefania"
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Item Evaluación de la actividad antimicrobiana de péptidos catiónicos vehiculizados en nano liposomas funcionalizados, frente a bacterias patógenas de alimentos.(Universidad Santiago de Cali, 2019) Cantor Pareja, Stefania; Oñate, Jose FernandoDuring recent years the resistance of pathogens present in food to antibiotics has been demonstrated. That is why, in this research project, the antimicrobial activity of the synthetic peptides Alyteserin 1C (WT) and its mutant product (ΔM) was evaluated in bacterial strains such as Staphylococcus aureus ATCC25923, Listeria monocytogenes ATCCbaa751, Salmonella typhi ATCC25922. Use of two procedures: modification of the antimicrobial peptides and vehiculization of the peptides in liposomes coated with cationic polymer Eudragit E100. The results showed the antibacterial activity of the peptides against the bacteria. However, after the encapsulation of the peptides in liposomes coated with Eudragit E-100, the antibacterial activity was reduced from 1000 to 2000 times against the strains of Listeria monocytogenes ATCCbaa751 and Escherichia coli ATCC25922