Browsing by Author "Bravo Ortega, Laura"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Reformulación en jabón de la formulación común del minoxidil (1-óxido de 2,6- diamino-4-piperidinopirimidina)(Universidad Santiago de Cali, 2025) Saavedra Chavarro, Bryan Felipe; Bravo Ortega, Laura; Ocampo Chaguendo, Dennis Mauricio (Director); Garzón Méndez, William Fernando (Director)Androgenic alopecia is a hair loss condition influenced by two key factors: genetics and hormones. The most well-knowntopical medication is minoxidil (2,6-diamino-4-(piperidin-1-yl) pyrimidine 1-oxide). However, due to its poor water solubility, commercial formulations typically contain propylene glycol, which can cause skin reactions such as irritation and dryness in some individuals. This project aims to reformulate the cosmetic product using a vehicle that minimizes adverse skin reactions by opting for a solid presentation. Four soap variants were developed, each containing a 5% concentration of minoxidil. Quality tests were conducted to evaluate these formulations' effectiveness, allowing the identification of the formulation 1 as the most suitable variant in terms of stability and physicochemical characteristics.