Browsing by Author "Ayala Astudillo, Daniel Alonso"
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Item Evaluación de la asociación entre la presencia del islote de patogenicidad CagA positivo de Helicobacter Pylori y el daño histológico en la población de Tumaco, Nariño con contraste del riesgo de cáncer gástrico(Universidad Santiago de Cali, 2025-12-09) Murillo Ferraro, Katherine Nicolle; Ayala Astudillo, Daniel AlonsoHelicobacter pylori is a microorganism that colonizes the gastric mucosa and is a key risk factor in the development of gastric cancer. The aim of this study was to analyze the relationship between the presence of the H. pylori cagA pathogenicity gene and gastric histological damage in the population of Tumaco, Nariño. Descriptive, univariate, and bivariate statistical analyses were performed using R Studio software, with a significance level of p<0.05. The results did not show a significant association between the presence of the cagA gene and the type of histological damage (p = 0.719; Fisher = 0.6198), nor with the variables gender (p = 0.7087; Fisher = 0.5517) and age. This study demonstrates the relationship between Helicobacter pylori and its CagA+ virulence factor in gastric damage, highlighting its role in the health of populations with a low risk of gastric cancer, such as Tumaco, Nariño.