A. Ramirez, Maria CamilaGubiani, Juliana R.L. Parra, Lizbeth L.C. Santos, Mario F.Williams, David E.D. Ferreira, DaianeT. Mesquita, JulianaTempone, Andre G.Ferreira, Antonio G.Padula, ViníciusHajdu, EduardoAndersen, Raymond J.S. Berlinck, Roberto G.2019-08-122019-08-1220170163-3864https://repositorio.usc.edu.co/handle/20.500.12421/534Marine sponges are a rich source of terpenoids with rearranged spongian carbon skeletons. Investigation of extracts from the sponge Darwinella cf. oxeata yielded four new rearranged diterpenoids, oxeatine (2) and oxeatamides H-J (3-5), as well as the known metabolites oxeatamide A (6), oxeatamide A methyl ester (7), and membranolide (1). Oxeatine (2) has a new heterocyclic skeleton, while oxeatamide J (5) has an N-methyl urea group included in a γ-lactam moiety. UPLC-QTOF analysis of the extract obtained from the mantle of the nudibranch Felimida grahami indicated the presence of 1 and 4.enArticle