Martinez Montalvo, Carlos MauricioForero Vargas, Daniel AndrésCabal Chilito, Natalia AndreaEstrada Serrano, NataliaMuñoz Bedoya, Kenny JulianaAchicanoy, Andrés FernandoVargas, Valeria BautistaNavarro Peña, María Teresa2025-04-022025-04-022022-10Martinez Montalvo, C. M., Forero Vargas, D. A., Cabal Chilito, N. A., Estrada Serrano, N., Muñoz Bedoya, K. J., Achicanoy, A. F., Vargas, V. B., & Navarro Peña, M. T. (2022). Disseminated gonococcal infection: Case report | Enfermedad gonocócica diseminada: Reporte de caso. Acta Medica Peruana, 39(4), 386–391. https://doi.org/10.35663/amp.2022.394.237910188800https://repositorio.usc.edu.co/handle/20.500.12421/6210Introduction: Infection by Neisseria gonorrhoeae (NG) is the second cause of sexually transmitted disease (ETS), with an increasing incidence, high rates of antibiotic resistance and with its greatest presentation at the genital level. Its presentation with bacteriemia is less than 3%, limiting its diagnosis due to its low performance. Therefore, we report the case. Case presentation: 60-year-old man with a history of diabetes mellitus, who was admitted due to polyarticular symptoms with synovitis, associated with a febrile syndrome, with no other finding on physical examination. Bacteremia due to Neisseria gonorrhoeae is documented, with a temporal link with previous sexual intercourse. Antibiotic treatment is indicated according to antibiogram with partner prophylaxis. Patient is discharged without any complications. Conclusion: Hematic dissemination by NG is a rare condition, with very non-specific initial symptoms, with low performance of diagnostic tests in this condition, which requires high clinical suspicion, and a very detailed clinical history is of great importance. As in our case, nonspecific symptoms led to ruling out other conditions until isolation in blood cultures leads to a definitive diagnosis. It is a case with unusual clinical presentationesNeisseria gonorrhoeaeGonorrheaBacteriemiaArticle